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PROTEINS

PROTEINS. Natural polymers C,H,O,N,(S) Monomer is Amino Acids Growth Repair Hormones Enzymes Antibodies Energy Source. PROTEINS. 15% of our bodies Composed of 20 amino acids 10 we cannot synthesise and store ( essential amino acids ) We get them from food

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PROTEINS

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  1. PROTEINS • Natural polymers • C,H,O,N,(S) • Monomeris Amino Acids • Growth • Repair • Hormones • Enzymes • Antibodies • EnergySource

  2. PROTEINS • 15% of ourbodies • Composed of 20 amino acids • 10 wecannotsynthesise and store (essential amino acids) • Wegetthemfromfood • A Complete Proteincontainsall 10 (egCasein)

  3. 2-amino acids • Containcarboxylgroup and amine (amino) group • Colourless • Crystallinesolids • Exist as Zwitterions • Therforehighm.p. • Soluble in water • Amphoteric

  4. Zwitterions

  5. Lysine • Basic amino acid

  6. AsparticAcid • Acidic amino acid

  7. Amino Acids • Amphotericnaturemakesitpossibletoact as buffers

  8. CondensationReaction

  9. PRIMARY STRUCTURE • Thesequence of amino acids • 3 lettercodesused • A tripeptidewouldhave 3 amino acids in sequence

  10. SecondaryStructure • Manner in whichproteinfolds • Intramoleculerhydrogenbondingimportant • Between O oncarbonylgroup and H on amine • Alpha-helix • Beta-pleatedsheets

  11. TertiaryStructure • Overall 3D shape • Covalentbonding (egdisulphide bridges) • H-bonding • Salt bridges (electrostaticattraction) • Affect of R group (egpolarity, hydrophobicinteractions)

  12. QuarternaryStructure • Howsubunitsjointogether • Haemoglobin

  13. Denaturing • Heat • Ionisingradiation • Strongacids, bases • Concentratedsaltsolutions • Organicsolvents • Detergents

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