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Response vs. Concentration Relationship Analysis in Biological Systems

Explore the impact of concentration on biological responses and outcomes, comparing positive and negative responses. Investigate the effects of log concentration and various inhibitors to understand complex mixed responses.

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Response vs. Concentration Relationship Analysis in Biological Systems

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  1. POSITIVE RESPONSE vs [CONCENTRATION] Outcome max [ML] [Y] Jo vo “RESPONSE” [L]free [X] [Ao] [S] [molecule]

  2. 1/RESPONSE vs 1/[CONCENTRATION] Outcome 1/[ML] 1/[Y] 1/Jo 1/vo “1/RESPONSE” 1/[L]free 1/[Ao] 1/[S] 1/[X] 1/[molecule]

  3. RESPONSE vs LOG [CONCENTRATION] Outcome max [ML] [Y] Jo vo “RESPONSE” log[X] log [L]free log[Ao] log[S] log [molecule]

  4. NEGATIVE (inhibitory) RESPONSE vs [CONCENTRATION] Outcome max comp -Inhib mixed [ML][Y]J0v0RESPONSE uncomp [L]free[ Ao][S][X] [molecule]

  5. 1/RESPONSE vs 1/[CONCENTRATION] Outcome + MIXED + COMP 1/[ML]1/[Y]1/J01/v01/RESPONSE + UNCOMP - Inhibitor 1/[L]free1/[A0]1/[S]1/[X] 1/[molecule]

  6. RESPONSE vs LOG [CONCENTRATION] Outcome max + COMP [ML][Y]J0v0RESPONSE NONCOMP + UNCOMP log [L]freelog[Ao]log[S]log[X] log [molecule]

  7. NEGATIVE (inhibitory) RESPONSE vs [CONCENTRATION] Outcome - Inhibitor Fixed [L], [Ao], [S], [X]non saturating [ML][Y]J0v0RESPONSE saturating [Inhibitor] – COMP, UNCOMP, NONCOMP

  8. RESPONSE vs LOG [CONCENTRATION] Outcome - Inhibitor [ML][Y]J0v0RESPONSE Fixed [L], [Ao], [S], [X]non-saturating saturating log [Inhibitor] – COMP, UNCOMP, NONCOMP

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