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Explore the various methods of transport across plasma membranes including simple diffusion, facilitated diffusion, and osmosis. Understand the principles of Fick's Law, osmotic pressure, and different tonicity states in solutions. Learn about the key molecules and hormones involved in membrane transport. Figures from Guyton and Hall provide visual aids for clarity. Discover the intricacies of movement through lipid bilayers and channels, as well as the factors influencing diffusion rates.
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Diffusion through lipid bilayer • CO2 • O2 • NO • Steroid Hormones • Monoglycerides
Fick’s Law • J = P.∆C • P = D.A/∆X • J = D.A.∆C/∆X J = Flux (Rate of diffusion) P = Permeability D = Diffusion Coefficient A = Surface area C = Concentration X = Membrane thickness
Facilitated Diffusion • Aminoacids • Glucose • Galactose • Fructose
Van’t Hoff’s Law π = RTC π : osmotic Pressure R = Gas constant T = Absolute Temprature C = Concentration
Hypotonic (cell swells) Isotonic (no change) Hypertonic (cell shrinks) Figure 25-5; Guyton and Hall