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PLASMA MEMBRANES. EVERY CELL HAS A CELL MEMBRANE. FUNCTIONS OF THE PLASMA MEMBRANE. REGULATES THE PASSAGE OF MATERIALS INTO AND OUT OF THE CELL RECEIVES INFORMATION FROM THE ENVIRONMENT MAINTAINS THE STRUCTURAL AND CHEMICAL RELATIONSHIPS OF THE CELL WITH ITS NEIGHBORS CELL PROTECTION
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PLASMA MEMBRANES EVERY CELL HAS A CELL MEMBRANE
FUNCTIONS OF THE PLASMA MEMBRANE • REGULATES THE PASSAGE OF MATERIALS INTO AND OUT OF THE CELL • RECEIVES INFORMATION FROM THE ENVIRONMENT • MAINTAINS THE STRUCTURAL AND CHEMICAL RELATIONSHIPS OF THE CELL WITH ITS NEIGHBORS • CELL PROTECTION • SECRETION • CELLULAR MOVEMENT • IMPULSE TRANSMISSION
REGULATES THE PASSAGE OF MATERIALS INTO AND OUT OF CELL • SELECTIVELY PERMEABLE • MAINTAINS A CONSTANT INTERNAL CONDITION DESPITE CHANGES IN EXTERNAL ENVIRONMENT
RECEIVES INFORMATION FROM THE ENVIRONMENT • RECEPTOR PROTEINS RECEIVE CHEMICAL MESSAGES • MEMBRANE IS STIMULATED TO SEND MESSAGE INTO CELL • CAUSES SOME TYPE OF RESPONSE
MAINTAINS THE STRUCTURAL AND CHEMICAL RELATIONSHIPS OF THE CELL WITH ITS NEIGHBORS • RECOGNITION • ADHERANCE • EXCHANGE OF MATERIALS • RESPOND TO FIRST MESSENGERS
OTHER FUNCTIONS • CELL PROTECTION • SECRETION • CELLULAR MOVEMENT • IMPULSE TRANSMISSION
THE FLUID MOSAIC MODEL OF THE PLASMA MEMBRANE • 6-10 NANOMETERS THICK • FLUID LIPID BILAYER • PROTEINS EMBEDDED • EACH LAYER IS CALLED LEAFLET
THE LIPID COMPONENTS OF THE PLASMA MEMBRANE • PHOSPHOLIPIDS • HYDROPHILIC • HYDROPHOBIC • GLYCOLIPIDS • CHOLESTEROL
PHOSPHOLIPIDS • MAIN COMPONENT OF MEMBRANES • PHOSPHATE AND GYLCEROL HEAD • FATTY ACID TAILS • VARY IN SATURATION
CHOLESTEROL • STEROID • FOUND BETWEEN PHOSPHOLIPIDS • AFFECTS MEMBRANE FLUIDITY
THERMOPHILES • HIGH TEMPERATURES • MAKES MEMBRANE LESS FLUID • RESTRAINS MOVEMENT OF PHOSPHOLIPIDS
PSYCHROPHILES • LOW TEMPERATURES • HINDERS PACKING OF PHOSPHOLIIDS • LOWERS TEMPERATURE FOR SOLIDIFICATION
LIPID BILAYER IS VERY IMPERMEABLE TO IONS AND POLAR MOLECULES • SERVE AS BARRIER TO IONS AND POLAR MOLECULES • WATER IS AN EXCEPTION • MOVES EASILY THROUGH MEMBRANE
TRANSPORT ENZYMATIC ACTIVITY SIGNAL TRANSDUCTION CELL TO CELL RECOGNITION INTERCELLULAR JOINING ATTACHMENT TO CYTOSKELETON AND EXTRACELLULAR MATRIX SPECIFIC FUNCTIONS OF MEMBRANE PROTEINS
TRANSPORT • http://www.miracosta.cc.ca.us/home/sfoster/neurons/membraneimt1.gif
PROTEINS IN THE CELL MEMBRANE • HYDROPHOBIC • HYDOPHILIC • INTEGRAL PROTEINS • PERIPHERAL PROTEINS
GLYCOPROTEINS • PROTEIN WITH ADDITION OF A CARBOHYDRATE • MOST OF PROTEINS ASSOCIATED WITH INNER SIDE OF MEMBRANE ARE GLYCOLIPIDS • SERVE AS COMMUNICATION SYSTEM WITH ENVIRONMENT • SOME ARE PERPIPHERAL PROTEINS • MAY FORM GLYCOCALYX
THE CELL MEMBRANE AND THE CYTOSKELETON • CYTOSKELETON GIVES SHAPE • COMPLEX INNER SCAFFOLDING
MICROVILLI • MANY CELLS HAVE FREE SURFACES • TINY EVAGINATIONS OF MEMBRANE • INCREASE SURFACE AREA OF CELL
MOVEMENT OF MATERIALS INTO OR OUT OF THE CELL • DEPENDS ON THE STRUCTURE OF THE MEMBRANE • DEPENDS ON THE SIZE AND CHARGE OF THE MOLECULES
SELECTIVELY PERMEABLE • ALLOWS SOME TO PASS THROUGH • BLOCKS OTHERS
MECHANISMS OF MOVEMENT • PASSIVE VS ACTIVE
PASSIVE MOVEMENT • DIFFUSION • SIMPLE DIFFUSION • THROUGH LIPID BILAYER • OR CHANNEL PROTEINS • FACILITATED DIFFUSION • USES CARRIER MOLECULES • OSMOSIS • SPECIAL TYPE • WATER ONLY
SIMPLE DIFFUSION • MOVE DUE TO RANDOM KINETIC ENERGY OF MOLECULES THEMSELVES • THE CELL DOES NOT EXPEND ENERGY
SIMPLE DIFFUSION • THE MOVEMENT OF PARTICLES FROM A REGION OF HIGHER CONCENTRATION TO A REGION OF LOWER CONCENTRATION DOWN A CONCENTRATION GRADIENT • INEFFICIENT PROCESS • USED BY EUKARYOTES MORE THAN PROKARYOTES
RATE OF DIFFUSION • DEPENDS ON • SIZE OF ATOMS OR MOLECULES • TEMPERATURE • STATE OF MATTER • SOLID • LIQUID • GAS
IMPORTANCE OF DIFFUSION • OXYGEN, CARBON DIOXIDE, WATER, OTHER SMALL MOLECULES CAN DIFFUSE INTO AND OUT OF CELLS EASILY • MATERIAL MOVE THROUGHOUT THE INTERIOR OF THE CELL BY DIFFUSION
FACILTIATED DIFFUSION • DIFFUSION THROUGH SPECIAL CHANNELS • ALLOWS HYDROPHILIC OR CHARGED MOLECULES TO PASS THROUGH MEMBRANE
IMPORTANCE OF CARRIER PROTEINS • ALSO CALLED TRANSPORT PROTEINS OR PERMEASES • SPECIALIZED TRANSPORT PROTEINS • ASSIST THE MOVEMENT OF MOLECULES THORUGH MEMBRANE • MOLECULES MOVE DOWN CONCENTRATION GRADIENT
CARRIER PROTEINS • EXTEND THROUGH MEMBRANE FROM EXTERIOR TO INTERIOR OF CELL • PROVIDE A WATER FILLED CHANNEL • RECEPTOR SITES SPECIFIC BIND TO ONE KIND OF MOLECULE • CARRIER PROTEIN CHANGES SHAPE • MOLECULE IS CARRIED INTO CELL
TRANSPORT PROTEINS • CHANNEL PROTEINS • AQUAPORINS • GATED CHANNELS • LIGAND GATED • ALSO CALLED CHEMICALLY GATED • ELECTRICALLY GATED
DIFFUSION IS A PASSIVE PROCESS • DOWN CONCENTRATION GRADIENT • DEPENDS ON RANDOM KINETIC ENERGY OF MOLECULE ITSELF
FACILITATED DIFFUSION IS SELECTIVE • CARRIER PROTEINS ONLY ACCEPTS CERTAIN TYPES OF MOLECULES
OSMOSIS • A SPECIAL TYPE OF DIFFUSION • IT IS THE DIFFUSION OF WATER MOLECULES FROM A REGION OF HIGH WATER CONCENTRATION TO AN AREA OF LOWWATER CONCENTRATION ACROSS A SEMIPERMEABLE MEMBRANE
PLASMA MEMBRANES SELECTIVELY REGULATE THE MOVEMENT OF MOST SOLUTES • WATER CAN MOVE FREELY THROUGH MEMBRANE
ISOTONIC SOLUTION • WHEN LIVING CELLS ARE PLACED IN A SOLUTION THAT HAS A SOLUTE CONCENTRATION EQUAL TO THAT IN THE CELLS, THE WATER MOLECULE CONCENTRATION IS ALSO EQUAL INSIDE AND OUTSIDE THE CELL • WATER MOLECULES WILL MOVE INTO AND OUT OF THE CELL AT THE SAME RATE
CELL IN AN ISOTONIC ENVIRONMENT • http://jcs.biologists.org/cgi/reprint/113/8/1365.pdf