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Cortical Structures of the Limbic System. Most notable structures Primary function Orbitofrontal gyri Very diverse Cingulate gyrus Emotion Isthmus Emotion + Memory Parahippocampal gyrus Memory Uncus Olfaction. Subcortical Structures of the Limbic System.
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Cortical Structures of the Limbic System Most notable structuresPrimary function Orbitofrontal gyriVery diverse Cingulate gyrus Emotion Isthmus Emotion + Memory Parahippocampalgyrus Memory Uncus Olfaction
Subcortical Structures of the Limbic System Most notable structures: Septal nuclei Nucleus accumbens Mammillary body Amygdala Dorsal thalamus Habenula Hippocampal formation Most notable efferent pathways: Fornix Striaterminalis Ventral amygdalofugal Mammilothalamic
Hippocampal Formation Afferent Pathways Perforant Alvear Fornix Efferent Pathways Fornix
Amygdaloid Complex Afferent Pathways Cingulum StriaTerminalis Lateral oflactorystria Efferent Pathways StriaTerminalis Amygdalofugal
Septal Nuclei & Nucleus Accumbens Septal Pathways MFB (A&E) Striaterminalis (A) Fornix (A&E) Striamedullaris (E) Nuc. Acc. Pathways MFB (A&E) Stria terminals (A) Fornix (A)
Learning and Memory • Associative Learning • Formation of associations between 2 features in the environment • Nonassociative Learning • Experience produces changes in the magnitude of the response
Cellular Mechanisms of Memory • Hebb’s Postulate: • Cells that fire together • wire together; Cells that • fire out of sync lose their • link • Long-Term Potentiation • Enhancement of synaptic efficacy following strong stimulation