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Effect of Intraoperative Aberrometry on the Rate of Postoperative Enhancement. Mark Packer, MD, FACS Clinical Associate Professor Oregon Health & Sciences University.
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Effect of Intraoperative Aberrometry on the Rate of Postoperative Enhancement Mark Packer, MD, FACS Clinical Associate Professor Oregon Health & Sciences University The author of this poster is a consultant with the following companies: Abbott Medical Optics, Advance Vision Science, General Electric, Rayner Intraocular Lenses, Transcend Medical, TrueVision Systems and WaveTec Vision Systems.
Purpose & Methods • To determine the effect of intraoperative wavefront-guided enhancement of limbal relaxing incisions on the rate of postoperative excimer laser enhancement • Retrospective chart review • Patients having limbal relaxing incisions (LRIs) at the time of cataract or RLE surgery • May 2007 to June 2009 • August 2008 ORange ( WaveTec, Inc., Aliso Viejo, CA) • Talbot moire interferometry • Fourier transform • Calculation of spectacle correction
Methods • Standardized LRI technique • Sim Ks (EyeSys, Tracey, Inc) • Nichamin nomogram • After IOL insertion (IOP ≥ 25 mm Hg) • 10 mm OZ • Ruminson Astigmatic Gauge and Marker (Rhein Medical, Tampa, FL) • 90% depth • Cornea Gage Plus (Sonogage, Cleveland, OH) • Stealth Triamond (Mastel Precision, Rapid City, SD) • Enhancement by extending arcs • measured axis ± 15º of expected • (SIA + 0.5 D @ 90º) • residual cylinder ≥ 1.0 D.
Results – Group 1 • 37 eyes of 27 patients • Not measured with intraoperative aberrometry • 63.5 ± 9.0 years • Mean pre op ∆K = 1.5 D (0.51 – 2.64) • Mean steep axis = 83º • Mean pre op 10 mm pachy = 679 µ • Post op MR Cyl at 33 days (n =36 ) = 0.48 D • Post op MR Cyl at 9 months (n = 20) = 0.53 D
Results – Group 2 • 30 eyes of 21 patients • Measured with intraoperative aberrometry • 61.5 ± 9.1 years • Mean pre op ∆K = 1.28 D (0.52 – 3.25) • Mean steep axis = 87º • Mean pre op 10 mm pachy = 668 µ • Post op MR Cyl at 24 days (n = 28) = 0.37 D • Post op MR Cyl at 5 months (n = 14) = 0.41 D
Postoperative Comparison Group 1 Group 2 Mean Sphere -0.27 -0.33 Mean MRSE +0.0 -0.15 Median UCVA 20/25 20/25 MR Cyl 0.48 0.37 ≥ 0.75 D 10 (27%) 7 (23%) ≥ 1.00 D 9 (24%) 2 (6.6%) ≥ 1.25 D 4 (11%) 1 (3.3%)
Group 2 – LRI Enhanced • 8 eyes of 6 patients • Enhanced with extended LRIs • 62.2 ± 12.5 years • Mean pre op ∆K = 1.75 D (0.87 – 3.25) • Mean steep axis = 82º • Mean pre op 10 mm pachy at steep axis = 655 µ • Post op MR Cyl at 29 days (n = 8) = 0.31 D • Post op MR Cyl at 6 months (n = 3) = 0.42 D
Group 1 – Laser Enhanced Without aberrometry (Group 1) 6/37 = 16.2% 59.8 ± 3.7 years Mean pre op ∆K = 1.70 D (0.76 – 2.32) Mean steep axis = 95º Mean 10 mm pachy at steep axis = 664 µ Before excimer at 2 - 11 months MRSE = -0.39 D (-1.1 – 0.38) MR Cyl = 1.45 D (1.0 – 2.5)
Group 2 – Laser Enhanced With aberrometry (Group 2) 1/30 = 3.3% 58 years Pre op ∆K = 2.61 D Steep axis = 78º Pre op 10 mm pachy at steep axis = 658 µ Before excimer (1 month) MRSE = -0.50 D MR Cyl = 1.00 D
Conclusion Intraoperative wavefront-guided enhancement of LRIs with ORange produced a trend reducing the rate of postoperative excimer laser enhancement from 16.2% to 3.3%, an odds ratio of 5.71 (p=0.12)