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HEALTH AND DISEASE. Prof. J. Hanacek, M.D., Ph.D.,. Health and disease – two essential categories of medicine Definition of health Health is defined as a state of optimal physical, mental, and social well-being and not merely
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HEALTH AND DISEASE Prof. J. Hanacek, M.D., Ph.D.,
Health and disease – two essential categories • of medicine • Definition of health • Health is defined as a state of optimal physical, mental, and social well-being and not merely the absence of disease and infirmity (according to W.H.O.) • Health can be defined as a „state“ of the person who is able to meet the demands placed on his/her body and to adapt to these demands or changes of the external environment so as to maintain reasonable constancy of theinternal environment
There is way of measuring health in a negative sense. It is measuredby the "5 ds" - death, disease, discomfort, disability, and dissatisfaction. If there is absence of 5 d‚s we can say that person is healthy ●In health there is freedom. Health is the first of all liberties! ● Holistic view to a health recognizes the inter relatedness of thephysical, psychological, emotional, social, spiritual,and environmental factors that contribute to the overall quality of a persons life
Two aspects of health can be distinguished: • Subjective – it is formed by sensations and feelings • of a person, e.g.highworking capacity,ability to • overcome problems, optimistic thinking, happiness, • satisfaction... • 2) Objective – its basis is formed by objective • parameters obtained by measurement of • strutures and functions of a person • Subjective and objective aspects of a health can differ • e.g. – Man with systemic BP can feel healthy • Oposite – Man can feel ill despite no measurable changes of • structure and/or functions can be find
Positive cosequence of WHO definition of health: –change of health care phylosophy Classik phylosophy: Diseased person doctor diagnosis therapy Modern phylosophy healthy person health promotion prevention of disease onset and development health protection
Two dimensions of health according Nordenfeld (1986) Scientistic = atomistic-biological dimension of health - quantitative dimension of life Non-scientistic = holistic-humanistic view on health - rather qualitative dimension of life - seeing health as the totality of a persons existence Summary: ● health is defined by set of objective, measurable parameters of structure and functions of the body ● health is defined also by set of subjective parameters expressed by healthy person
Positive wellness involves: 1. being free from symptoms of disease and pain as much as possible; 2. being able to be active - able to do what you want and what you have to do at the appropriate time; 3. being in good spirits most of the time
Concept of normalcy Norm(normal,within the norm) = parameters or values ranging from-toof bodily or mental functions or quantitative measurements of biologicalindexes derived statistically from "healthy persons" of the specific group (hight, body mass, heartrate, respiration rate,blood pressure, body temperature, etc.) Norm Health; Health =Norm Health – it is more qualitative term Norm – it is more quantitative term Normal parameter – parameter presents most frequently in healthy population
Interindividual variability: – each person has its own profile of structures and functions, and almost each person is extreme in some of sign, and in different one – in population is created by influence of many factors: a) internal – mainly genetic b) external – physical, chemical, biological, social... – can be one explanation for different level of health in different people, and different proneness to disease
Definitions of disease • Disease can be defined as a biosocial phenomenon characterizedbyinteractions of pathological processes,defensive and adaptation processes resulting in damage of the organismas a whole, in limitation of the organism ability to adapt to livingcondition. • Disease can be defined as a changes in individuals that cause theirhealth parameters to fall outside the range ofnormal • The term disease means a deviation from or an absenceof the normal state
The essential aspects of disease • disease is a new quality of life • Health is a friedom, disease is a prison 2. disease is the result of one or more causes (noxas) and suitable conditions 3. disease is the unity of damaging, adaptive, defensive and compensation mechanisms
A picture of diseaase is created by: – pathologic reactions – pathologic processes – pathologic states • Pathologic reaction • It is the most simple, mainly short-lasting, • quantitativly and/or qualitativly non-adequate • response of organisms to some noxa • Examples: syncopa, short-lasting increase of BP, • tachycardia, bradycardia, vomiting, • diarhoe, hyperventilation ...
Pathologic process It is the complex of pathologic and defensive- - adaptive reactions induced by influence of noxa on organism Examples: inflammation, fever, hypoxia, growth of tumor, edema, acidosis, alkalosis... Pathologic state Pathological change which is stabile or it changes very slowly and in very small range during time period Examples: congenital valvular heart disease, deafness, blindness, colour blindness...
Dynamics of disease Disease is a definite morbid process haveing a characteristic train of symptoms and signs Dynamics of disease is characterized by stages of disease: 1st stage:latent – incubation (in infections diseases) Its duration is measured by time passed between beginning of noxa influence of body and beginning of first non-specific symptoms and signs of disease There are no manifestations of disease during this stage 2nd stage: prodromal First non-specific symptoms and signs of disease arise
3rd stage: manifestation of disease There arespecific symptoms and signs characteristic for specific disease 4th stage: disease outcomes a) healing and convalescence b) chronic disease c) death • Forms of healing: • restitutio or sanatio ad integrum • sanatio per compensationem
Time course of disease • Peracute – onset during few seconds or minutes • Acute – onset during hours and days, duration up to • 3 weeks • Subacute – duration up to6 weeks • Chronic – duration more than 6 weeks Exacerbation of disease – usually sudden increse intensity of symptoms and signs of chronic disease Recidivation of disese – returning of previosly healed disease Remision of disease: decrese intensity of simptoms and signs of disease
ILLNESS AND DISEASE It is more important to know what sort of patient has a disease, than what sort of disease a patient has A person may "feel ill" without a disease being evident or diagnosed;likewise, a person may have a disease without experiencing any illness or suffering Illness tends to be used to refer to what is wrong with the patient, disease to what is wrong with his body ●Illness is what the patient suffers from, what troubles him, what be complains of, and what prompts him to seek medical attention
●When we say "a person is ill " we mean he feels uncomfortable, he is suffering from certain symptoms such as nausea, headache, abdominal cramps, or just fatigue that can't be explained on thebasis of exertion ●Disease refers to various structural disorders of the individuals tissues and organs that give rise to the signs of ill - health
The principal factors accounting for nearly all diseases are: 1. heredity - inherited (genetic) diseases, 2. infectious organisms - infectious diseases, nosocomial disease 3. lifestyle and personal habits - lifestyle diseases 4. accidents 5. physical, chemical noxas (poisons and toxins)
Most standard medical textbooks attribute anywhere from 50 to 80% of all disease to psychosomatic or stress-related origins Examples of psychosomatic diseases: - peptic ulcer, essential hypertension, bronchial asthma, hyperreactive thyroid, rheumatoid arthritis, ulcerative colitis..... Partially or wholly psychosomatic disorders: hay fever, acne, diarrhea, impotency, warts, eczema, tinnitus, bruxism (grinding of teeth), nail biting, tension headaches, back pain, insomnia.....
Psychosomatic illness are caused by negative mental statesand attitudes that harmfully change the physiology • Psychosomatic illness are real - as real as appendicitis or pneumonia • Placebo effect = the healing that results from a persons belief in substances or treatments that have nomedical value in themselves The power of healing does not reside so much in the healer as in the belief of the patient. The cures that results from placebo effects sometimes seem miraculous but actually are caused by physiological changes brought about by peoples beliefs and mental states. The mind is healer!!!
Relation: disease - punishment In nature there are neither rewards nor punishments - only consequences All manifestations of human disease are the consequence of the interplay between body, mind, and environment