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12-4 Mutations

12-4 Mutations. Pg. 307. A. Kinds of Mutations. 1. Mutations are changes, or mistakes, made in the genetic material. 2. Types of Mutations: Point Mutations Frameshift Mutations Silent Mutations. A. Kinds of Mutations. 3. Point Mutations involve a change in one or a few nucleotides.

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12-4 Mutations

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  1. 12-4 Mutations Pg. 307

  2. A. Kinds of Mutations • 1. Mutations are changes, or mistakes, made in the genetic material. • 2. Types of Mutations: • Point Mutations • Frameshift Mutations • Silent Mutations

  3. A. Kinds of Mutations • 3. Point Mutations involve a change in one or a few nucleotides.

  4. A. Kinds of Mutations • 4. Frameshift Mutations shift the “reading” frame of genetic code by inserting or deleting a nucleotide.

  5. Label: Point or Frameshift • 1. AAG-GGG  AUG-GGG • Lysine-Glycine Methionine- Glycine • 2. UUC  AUUC • Phenylalanine  Isoleucine • 3. AGC-CCC  AGC-CGC • 4. UUAG  UAG

  6. A. Kinds of Mutations • 5. Silent Mutations have no observable effect on an organism.

  7. B. Significance of Mutations • 1. Negative • Cancers • Genetic Diseases • Ex: Sickle Cell Disease and Cystic Fibrosis

  8. B. Significance of Mutations • 2. Positive • Resistance to Diseases • Physical Advantages • Example: Plant and animal breeders

  9. Word Bank: Mutations, Genetic Diseases, Frameshift, Positive, Effects, Types, Point

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