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caBIG ® Clinical Information Suite West Michigan Cancer Center Domain Expert Meeting Oct 27-28, 2010. Announcements, Introductions, & Updates. Wednesday, October 27, 2010. Announcements, Introductions, and Updates. Topic Agenda Wednesday October 27 . Topic Agenda Thursday October 28 .
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caBIG® Clinical Information SuiteWest Michigan Cancer CenterDomain Expert Meeting Oct 27-28, 2010
Announcements, Introductions, & Updates Wednesday, October 27, 2010 Announcements, Introductions, and Updates
caBIG Clinical Information Suite – Therapeutics Chemotherapy Management
caBIG Clinical Information Suite Domain Analysis Model
DAM Changes Review • Outcomes Models • Encounter • Changes to Treatment Plan • Concerns • Allergies • Cancer
Modeling Chemotherapy Activities • There are three activities normally associated with an administration activity: • The Order • The Supply • The actual Administration • “Normal” prescriptions make the order and supply explicit but the administration is implicit and assumed. • We assume because you picked up your Crestor that you are actually taking it as told • Immunizations have an explicit administration with an implicit supply, but not very often an order • We have international use cases for an immunization order • Chemotherapy? • My first guess: an Order and an Administration with an implicit supply
caBIG Clinical Information Suite – Diagnostics Cancer Staging
Cancer Staging Discussion • AJCC 7th Edition 1. ‘Staging Group’ = ‘Anatomic Stage/Prognostic Groups’ • Anatomic Stage (Stage IIIB) • Prognostic Factors (HER2 status . . .) 2. Subtle but important changes on rules! 3. EHR cancer staging vs. Cancer Registry • Summary Staging? 4. Generalization back to Breast Cancer model
AJCC 7th • Some changes in TNM • Changes in terminology (6th Staging Group, in 7th is Anatomic Stage/Prognostic Group)
Anything missing? • Method used for staging (clinical vs. pathologic) • Histologic is pathologic, not clinical • Imaging stuff is clinical, not pathologic • Not consistent which has more information • Both will be recorded • Laterality – where would it come from? (ICD-9-CM); quadrant on breast seems to be important for billing, as well as proximity to nipple; does not actually affect actual stage • With neo-adj, may get pathology after chemo • ypT, ypM, ypN
Need a “field” for “Mitotic rate” • Duke (for colorectal)? Don’t support using? • Siewert? Sounds like it is used to figure out which body site to use for AJCC • Need a capability to add new staging systems in the future, but it needs to have controls to prevent tweaking AJCC • How to model current RI to support such future extension?
All sarcomas use “grade” in staging • Gyno has FIGO, but it’s been mapped to AJCC • Substaging for various areas, but still AJCC • Gestational trophoblastic tumors are not staged exactly the same way as other areas, as the relay on some clinical lab results; also age, antecedant pregnancy, others • Whitmore-Jewitt is Bladder (very old?); use AJCC • CNS – Glioma has no staging (diffused or focal); some have WHO system (grade 1-4); rely on pathology report, other standard reports • Genetic markers? Not ready to go there • Lymphoma - there are masses that can be measured, as well as liquid; TNM doesn’t work the same (you don’t use it); AJCC has taken over Ann Arbor staging system (A and B) • IPI – Int’l Prognostic Indicator
Leukemia – non-solid (skip)\ • Present DE group don’t practice pediatric oncology • Will look at vetting with larger SEG group • St. Judes may be a good contact
Cancer Staging Discussion • Source report traceability– expand on topic • What would be useful? • As long a particular document or image can be selected to link back to staging data (possibly T,M, or N separately), that would be ideal • Reporting needs • Report to problem list • Auto-populate in notes • Referrals • Scope statement document in progress
Topic: “restaging” • AJCC 7th supports a restaging concept with “r” prefix (cancer returns after disease-free state); will this really be used? Not sounding like it, would be fine with an indicator • Other issue: disease progresses (i.e., spreading to other organs/sites)
caBIG Clinical Information Suite – Therapeutics Chemotherapy Management
Next Steps? • Planning for next steps • Questions? • Big Thank you!