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Skin as an organizing model. What is it? (Anatomy) What does it do? (Physiology ) What is it made of? (Histology ) Where does it come from? (Embryology). What is it (anatomy)?. Outer covering of body Keratinized Hair—head, pubic regions Nails—fingers, toes
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Skin as an organizing model What is it? (Anatomy) What does it do? (Physiology) What is it made of? (Histology) Where does it come from? (Embryology) Frolich, Human Anatomy, Skin
What is it (anatomy)? • Outer covering of body • Keratinized • Hair—head, pubic regions • Nails—fingers, toes • Divided into segments called dermatomes (“Zebra-man”) • CE (clinical example): Shingles Frolich, Human Anatomy, Skin
What does it do (physiology)? • [brainstorm] Frolich, Human Anatomy, Skin
What does it do? • PROTECTION • Air = desiccation • Water = bloating/”pruning” • Sun/u-v = burns • Cold/heat = frostbite/heat stroke/thermoregulation • STRUCTURAL • Integrity of body • Muscle attachment Frolich, Human Anatomy, Skin
How does it do it? • PROTECTION (mostly epidermis) • Desiccation—keratin, lipid layer • Water = keratin, lipid layer • Sun/u-v = role of pigment/melanin • Cold/heat = surface blood vessels • STRUCTURAL (mostly ddermis) • Integrity—Dermal layer has network of tough collagen fibers in connective tissue • Sub-dermal layer where muscle tendons insert Frolich, Human Anatomy, Skin
What is it made of?(histology—study of tissues) • Layers of skin are two fundamental types of tissue organization • Epidermis = epithelium • Dermis = connective tissue Frolich, Human Anatomy, Skin
Epidermis—a stratified epithelium Frolich, Human Anatomy, Skin
Dermis—connective tissue substrate Frolich, Human Anatomy, Skin
Skin is really an organ… • Made up of two very different basic tissue types • the epidermis which is composed of epithelial tissues • The dermis which is composed of connective tissue On to a review of basic tissue types… (“Tissues” presentation) Frolich, Human Anatomy, Skin
Where does it come from (Embryology) After review of basic tissue types, on to introduction to embryology and basic human body plan • outer and inner tubes of body (skin as epithelial layer and part of skeletal structure of outer tube) • Segmentation (skin reflects basic segmented organization of human body seen in vertebrae, ribs, nerves, etc.) (“Basic Human Body Plan” presentation) Frolich, Human Anatomy, Skin