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Impairment of Safe Sex Behavior by Women in an STD/HIV Prevention Trial

This study examines the impact of partnering with multiple sexual partners ("Players") on safe sex behavior and infection rates among women in an STD/HIV prevention trial. The findings highlight the reduced likelihood of safe sex practices and the increased vulnerability to male control among women partnered with "Players."

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Impairment of Safe Sex Behavior by Women in an STD/HIV Prevention Trial

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  1. Partner Impairment of Safe Sex Behavior by Women Participatingin a Randomized, Controlled STD/HIV Prevention Trial Alan E. C. Holden Ph.D. Sondra T. Perdue Dr.PH. Rochelle N. Shain Ph.D. Jeffrey E. Korte Ph.D. Jeanna M. Piper M.D. Jane D. Champion Ph.D. Holden@UTHSCSA.Edu

  2. Project S.A.F.E. • Randomized, controlled trial - behavioral/cognitive intervention to reduce STD recurrence - high-risk minority women (active STD) - San Antonio, Texas (1991-1995) • Significantly reduced STD reinfection at 6 and 12 months and cumulatively by reducing high-risk sexual behavior • Shain et al. NEJM 1999; 340:93 and • Shain et al. STD 2002; 29:9

  3. Procedure • 477 Women with complete data • Information about sexual partners (up to 5) at each time point (total 893 partners) • We identified “Players”: men having sex with more than one participant in our study by matching his initials, age, ethnicity, & other characteristics • Analysis: chi-square, logistic regression “Players” is the term used in the community

  4. Identification Procedure Results • Of 893 reported sexual partners: - 78 (“Players”) partnered with 2-4 women - appear 204 times in data set - 10.2% of all men • Remaining partners: 689 men • Of 477 women: - 46 (9.2 %) partnered with Players

  5. Characteristics of Players Compared to Other Partners1 Characteristic Players Others P-Value Steady partner 20.5% 53.8% < .01 Street drug use2 79.2% 34.8% < .01 Prior STD giver 46.2% 20.5% < .01 Has other partners 66.7% 17.8% < .01 Age > 25 51.3% 38.6% < .05 1 worst-case across multiple time points when applicable 2 excludes marijuana

  6. Players vs. Others: Infection Rates During 1-Year Follow-Up Overall Infection Rate = 21.6 % OR = 3.23 (CI 1.72-6.06) p < .01

  7. Unsafe Sex: • Never uses condoms in casual sex and/or • High number of unprotected acts (5+ in last 3 months) coupled with problematic condom use

  8. Problematic Condom Use: Condom use with: • Incomplete coverage of the penis • Condom slippage • Condom breakage • Other reported problems (e.g. stuck inside her)

  9. Unsafe vs. Safe Sex: Infection Rates During 1-Year Follow-Up OR = 3.44 (CI 2.19-5.40) p < .01 Shain et al. STD 2002; 29:9

  10. Players vs. Others: Unsafe Sex, No Condom Use, and Problematic Condom Use P < .08 P < .02 P < .01 n = 46 n = 431 n = 46 n = 431 n = 15 n = 208 Overall Unsafe Sex No Condoms Problematic Use

  11. Reasons Most Frequently Given by Women for No Condom Use Others unexpected coitus 18.5 % no condoms 15.2 % mutual trust 11.7 % she loves him 8.3 % erectile problems 2.6 % Players • he said he was clean 14.4 % • she was drunk/high 9.1 % • he refused 7.2 % • he forced sex 4.6 % • he promised he 3.5 % would “pull out”

  12. Players vs. Others: Vulnerability to Male Control P = .07 P = .08 He has a lot of influence over me Usually have sex when disagree

  13. Players vs. Others: Infection Rates among Women Practicing Unsafe and Safer Sex Mantel-Haenszel Common OR = 2.89, p < .01 n = 24 n = 148 n = 22 n = 283 Unsafe Sex Safer Sex

  14. WAS THERE AN INTERVENTION EFFECT?

  15. Study vs. Control Women: Partnering with Players during One-Year Follow-Up OR = 0.61 (CI 0.40-0.96) p = .034

  16. Intervention Results: Women Infected with Gonorrhea and/or Chlamydia, 1-Year Follow-Up OR = 1.63 (CI 1.05-2.53) p = .03 Shain et al. NEJM 1999; 340:93

  17. Study vs. Control Women: Unsafe Sexwhen Partnered with Players and Others Mantel-Haenszel Common OR = 2.89, p < .01 n = 17 n = 232 n = 29 n = 199 Study Group Control Group

  18. Study vs. Control Women: Reinfection during Follow-up when Partnered with Players and Others Mantel-Haenszel Common OR = 1.52, p < .07 n = 17 n = 232 n = 29 n = 199 Study Group Control Group

  19. Conclusions: • Women partnered with “Players” are: - less likely to practice safe sex: no condom use and/or incorrect condom use - more vulnerable to his influence and control • Study women are less likely than Controls to be partnered to “Players” during one-year follow-up

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