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Chapter 11. Caffeine. Caffeine. Caffeine is the most frequently consumed stimulant in the world It is classified as a xanthine (methylxanthine) It is found in a number of beverages Also found in some OTC medicines
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Chapter 11 Caffeine
Caffeine • Caffeine is the most frequently consumed stimulant in the world • It is classified as a xanthine (methylxanthine) • It is found in a number of beverages • Also found in some OTC medicines • In the U.S., the average daily intake of caffeine is equivalent to 2 cups of coffee a day.
Beverage Caffeine Content (mg)/cup Amount Brewed coffee 90-125 5 oz. Instant coffee 35-164 5 oz. Decaffeinated coffee 1-6 5 oz. Tea 25-125 5 oz. Cocoa 5-25 5 oz. Coca-Cola 45 12 oz. Pepsi-Cola 38 12 oz. Mountain Dew 54 12 oz. Chocolate bar 1-35 1 oz. Caffeine Content of Beverages and Chocolate
Coffee • Goatherd to holy man • “The women’s petition against coffee” • Tax • Consumption increased during prohibition • Commercial roasting began in 1790 • Starbucks
Tea • 350 AD • English East India Company • Popular in new colonies • Boston Tea Party
Chocolate • Cocoa • 17th century spread to wealthy in Europe • Drinks and houses • Bars
Other Sources Of Caffeine • Soft drinks • Energy drinks • Over the counter pills • Other natural sources
Effects of Xanthines • CNS effects • Enhances alertness, causes arousal, diminishes fatigue • Adverse CNS effects • Insomnia, increase in tension, anxiety, and initiation of muscle twitches • Over 500 milligrams - panic sensations, chills, nausea, clumsiness • Extreme high doses (5 to 10 grams) - seizures, respiratory failure, and death
Effects of Xanthines • Cardiovascular effects • Low doses - heart activity increases, decreases, or do nothing • High doses - rate of contraction of the heart increases, minor vasodilation in most of the body, cerebral blood vessels are vasoconstricted • Respiratory system effect • Can cause air passages to open and facilitate breathing
Caffeine • Caffeine Intoxication • Caffeinism: restlessness, nervousness, excitement, insomnia, flushed face, diuresis, muscle twitching, rambling thoughts and speech, stomach complaints • some research shows a relationship with: • cancers of the bladder, ovaries, colon, and kidneys • mammilary cysts • Caffeine Dependence
OTC Drugs Containing Caffeine • Analgesics • Stay awake products • Picker-uppers • Herbal Stimulants • Ephedrine