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Variable Pulsed Light (VPL TM ) for treatment of facial acne vulgaris

Variable Pulsed Light (VPL TM ) for treatment of facial acne vulgaris. George Badavanis , MD, PhD Dermatologist - Venereologist Private Practice, Mitilini , Greece This work was not supported by any direct or non direct funding. It is under the author’s own respons i bility

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Variable Pulsed Light (VPL TM ) for treatment of facial acne vulgaris

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  1. Variable Pulsed Light (VPLTM) for treatment of facial acne vulgaris George Badavanis, MD, PhD Dermatologist - Venereologist Private Practice, Mitilini, Greece This work was not supported by any direct or non direct funding. Itis under the author’s own responsibility Dr George Badavanis, Eresou 2 str, Mitilini, 81100 Tel - Fax +30 2251037390, e-mail: gbad@otenet.gr PRESENTED IN IMCAS ANNUAL MEETING 2010, JANUARY 8-11, PARIS

  2. Results All patients revealed a significant decrease in the numbers of inflammatory [80%; (p<0,001)], non-inflammatory [66%; (p=0,001)] and total acne lesions [74%; (p<0,001)] (Figures 2-5). The numerical reduction of the inflammatory lesions in 75% of patients was more than 75%, in 17% of them ranged between 50% and 75%, and in 8% between 25% and 50% (Figure 6). The decrease of non-inflammatory lesions was more than 75% in 25% of the patients, between 50%-75% in 67%, and between 25% and 50% in 8% of patients (Figure 7). 58% of the patients had more than 75% reduction of the total number of acne lesions, whereas the rest 42% of them had a reduction between 50% and 75% (Figure 8). In all patients an improvement of 1-2 acne clinical stages (mean 1,42 ± 0,51) was observed (Figures 9-13). Apart from a transient erythema (less than 1 hour duration) in 2 cases, no adverse reactions were observed. No patient experienced pain during or after treatment.

  3. Figure 9. Before and after 6treatments Figure 10. Before and after 5treatments

  4. Figure 11. Before and after 3treatments Figure 12. Before and after 4treatments

  5. Figure 13. Before and after 3treatments

  6. Conclusion It is out of question that topically or systemically applied drugs are the mainstay of acne therapy. Nevertheless, their side effects, contraindications, interactions and limitations (e.g. antibiotic-resistant P.acnes) justify the search for new effective, safe, painless and easy to perform therapeutic regimens. The results of the present pilot study indicate that VPL is an effective, safe and rapidly acting alternative therapy for female patients with acne vulgaris, particularly for those who are intolerant to or have contraindications for application of retinoids or other conventional therapies. However, further and controlled studies in large numbers of patients are now warranted that will precisely define the therapeutic efficacy and safety of VPL in the treatment of acne.

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