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Skeletal Systems. How do animals move? Passive Active: Locomotion swimming Terrestrial Flying Efficiency of each. Functions of Skeletal System Three types of skeletal systems Hydrostatic Exoskeleton Endoskeleton Invertebrates (echinoderms) Vertebrates (vertebrates).
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How do animals move? • Passive • Active: • Locomotion • swimming • Terrestrial • Flying • Efficiency of each
Functions of Skeletal System • Three types of skeletal systems • Hydrostatic • Exoskeleton • Endoskeleton • Invertebrates (echinoderms) • Vertebrates (vertebrates)
Functions of Skeletal System • Protection • Support • Reservoir of minerals – esp. Ca and P • Framework against which muscles operate
Exoskeletons • Calcium carbonate • mollusks • Chitin • Polysaccharride of modified glucose molecules • Leathery stiff with Calcium carbonate • Water impermeable • Varies in thickness • Secretion of epith. Cells • Requires molting – ecdysis – during growth • arthropods
Endoskeletons • Spicules bound by protein filaments • Echidoderms • Bone and/or cartilage
Two Types of Osseous Tissue • 1. Compact bone • Osteon – Basic unit • 2. Spongy Bone • Trabeculae provide bracing effect • Red Marrow produces blood cells
Osteon – Compact Bone Canaliculi Concentric lamellae Central canals Osteon Lacunae Light micrograph of an osteons
The Skeletal System • Axial Skeleton • 80 bones • skull, hyoid, vertebrae, ribs, sternum, ear ossicles • Appendicular Skeleton • 126 bones • upper & lower limbs and pelvic & pectoral girdles
Types of Bones – Shape General Characteristics, Examples • Long Bone • Flat Bone • Sutural Bones • Irregular Bone • Short Bone • Sesamoid Bone
Anatomy of a long bone: Diaphysis Epiphysis Metaphysis epiphyseal plate/line Periosteum Medullary cavity endosteum
Joint capsule Cellular layer of periosteum Cellular layer of periosteum Fibrous layer of periosteum Fibrous layer of periosteum Compact bone Endosteum • Periosteum: - 2 layers: • Outer (fibrous) • inner (cellular) • Collagen fibers continuous with: • Bone • adjacent joint capsules • tendons and ligaments
Trabeculae of Spongy Bone • oriented along lines of stress - Latticework • Harbor and protect red marrow ( blood cells develop) • Ends of long bones + inside flat bones No true Osteons.
Cells of Osseous Tissue • Develop/repair from cartilage, respond to stress, hormonal changes • Cells: • Osteocytes = mature bone cells – in lacunae • Osteoblasts: build – create osteoid during osteogenesis • Osteoprogenitor cells osteoblasts • Osteoclast – breakdown bone – osteolysis • Hormonal regulation
Rickets and Osteomalacia • Disorders resulting in abnormal/poor ossification • Rickets: (Children) • Vitamin D deficiency • Bowed limbs • Pain • Limbs easily broken • Osteomalacia • Failure of adult bone to ossify • hip fractures are common • most common in elderly SE Asian
Bone Development – Two Ways: 1) Intramembrannous – bone formed between sheets of connective tissue as skull bones 2) Endochondral – formed from hayaline cartilage model – long bones
Long Bone Growth • Epiphyseal growth – increases in length • Appositional Growth – increase in diameter
Bone Growth in Width • Only by appositional growth at the bone’s surface • Periosteal cells differentiate into osteoblasts and form bony ridges and then a tunnel around periosteal blood vessel. • Concentric lamellae fill in the tunnel to form an osteon.
Bone Growth in Length • Epiphyseal plate or cartilage growth plate • cartilage cells are produced by mitosis on epiphyseal side of plate • cartilage cells are destroyed and replaced by bone on diaphyseal side of plate • Between ages 18 to 25, epiphyseal plates close. • cartilage cells stop dividing and bone replaces the cartilage (epiphyseal line) • Growth Hormone controls activity of cells involved • Growth in length stops at age 25
Factors Affecting Bone Growth • Nutrition • adequate levels of minerals and vitamins • calcium and phosphorus for bone growth • vitamin C for collagen formation • vitamins K and B12 for protein synthesis • Sufficient levels of specific hormones • during childhood need insulinlike growth factor • promotes cell division at epiphyseal plate • need hGH (growth), thyroid (T3 &T4) and insulin • sex steroids at puberty • growth spurt and closure of the epiphyseal growth plate • estrogens promote female changes -- wider pelvis
Dynamic Tissue • Remodeling –a continuous process of breakdown and rebuilding • Osteoclasts: break bone down • Osteoblasts: replacement of bone • continues through adult life • distal femur is fully remodeled every 4 months
Sagittal suture Parietal bone Anterior fontanel LE 6-18c Coronal suture Frontal suture Frontal bone Frontal suture Anterior/superior view
Spinal Curves Present at Birth Thoracic sacral Develop after birth cervical Lumbar Abnormal Curves Scoliosis Lordosis Kyphosis
3________ 2________ 1________ 6-33
Intervetebral Discs: • Absorb vertical shock • Limited movement - • Fibrocartilagenous ring / pulpy center • Vertebral Canal • Interconnected vertebral foramina • Intervetebral Foramina • Passage for spinal nerves
Pectoral Girdle • Articulates with humerus • Where is the only direct articulation between pectoral girdle and axial skeleton? • Characteristics: • High mobility – low stability: elevation, depression, Also – retraction, protraction • Secured to axial skeleton via ligaments, muscles
Pelvic Girdle • Paired ossa coxae (singular: os coxae) • Composite bone: ilium, ishium and pubis • Join at pubic symphisis • Male versus female – easily observed –
Pelvic brim: bony edge of true pelvis • Pelvic inlet: an opening enclosed by pelvic brim • Pelvic outlet: circumference bounded by coccyx, ischial tuberosities, inferior pubic symphysis • Perenium: region of pelvic outlet in life – reinforced by muscles in life
Joints: • Arthrology – Study of Joints • Kinesiology = study of motion
Arthrology- Classification of Joints In Two Ways 1. Structural classification based upon: • presence of space between bones • type of connective tissue holding bones together • Fibrous: fibrous connective tissue • Cartilaginous: fibrous or hyaline cartilage • Both are Synarthrosis or amphiarthrosis –offer no or little movement • Synovial • Diarthrosis = free movement 2. Functional classification based upon movement: • immovable = synarthrosis • slightly movable = amphiarthrosis • freely movable = diarthrosis
Synovial Joints • Synovial cavity separates articulating bones • Freely moveable (diarthroses)
Features of Synovial Joints • Articular cartilage at ends of bone • Articular capsule encloses joint • Thickenings ligaments • Synovial membrane lines capsule • Synovial Fluid lubrication, nourishment, shock absorption • Accessory ligaments within and outside joint capsule • Articular discs or menisci at edges of capsule improve fit and stabilize joint • Bursae = saclike structures reduce friction – ‘ball bearings’
Articular Cartilage • Jelly-like, water squeezes out under pressure • Provides lubrication in joint – but how? • Microscopic dimples may help • dynamics of cartilage coupled with construction of joint play a part • Attacked/broken down arthritis
Arthritis • Inflammation of a joint - + 100 kinds • Osteoarthritis – degeneration of joint surfaces due to wear • Rheumatoid arthritis – inflammation of synovial membrane due to autoimmune disease • Drugs (Ibuprofen, Celebrex, Vioxx) – inhibit prostaglandins which trigger inflammation
Types and Complexity of Motion • Linear motion – gliding • Monaxial • Biaxial • Angular motion • Angle between shaft and surface changes • Monaxial – hinge joint • Biaxial – saddle joint • Triaxial - ball and socket joint • Rotation • Spinning of shaft on longitudinal axis – atlas and axis,
Flexion, Extension & Hyperextension Tortora & Grabowski 9/e 2000 JWS
Abduction and Adduction Condyloid joints Ball and Socket joints Tortora & Grabowski 9/e 2000 JWS
Circumduction • Movement of a distal end of a body part in a circle • Combination of flexion, extension, adduction and abduction • Occurs at ball and socket, saddle and condyloid joints Tortora & Grabowski 9/e 2000 JWS
Rotation • Bone revolves around its own longitudinal axis • medial rotation is turning of anterior surface in towards the midline • lateral rotation is turning of anterior surface away from the midline • At ball & socket and pivot type joints