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E-Seminar Protocols. As a courtesy to others, please mute your phone line while listening. Press *6 to mute (listen) Press #6 to un-mute (ask a question). 6 March, 2007 Presented by Tim Peck. One-Minute NMR 2007 demo tour. University of Buffalo: Buffalo, NY; January 8
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E-Seminar Protocols As a courtesy to others, please mute your phone line while listening Press *6 to mute (listen) Press #6 to un-mute (ask a question)
6 March, 2007 Presented by Tim Peck One-Minute NMR2007 demo tour • University of Buffalo: Buffalo, NY; January 8 • TriMR Regional Meeting: Research Triangle Pk, NC; Feb 15-16 • Southwest Regional Demonstration, San Diego, CA; Mar 27 (anticip) • ENC: Daytona Beach, FL; April 22 – 26 (anticip) • Schedule a live demo in your area! Call Protasis for details.
Metabonomics Research DayUniversity of Buffalo AmherstJanuary 8, 2007 Natural Sciences Complex Center for Tomorrow
Metabonomics and Top-Down Systems Biology: From Personalized Healthcare to Molecular Epidemiology Effects of Ligand and Ability to Lower Blood Glucose on Global Gene Expression in STZ-Diabetic Rats Treated with Oxovanadium Compounds Plenary Speaker: Professor Jeremy Nicholson 1H-NMR Metabonomics for Detecting Epithelial Ovarian Cancer Dr. Kunle Odunsi Dept of Gynecologic Oncology RPCI Prof. Gail Willsky Dept of Biochemistry Univ. Buffalo Prof. Frank Schroeder Cornell University and Harvard Medical School The virtue of the impure: chemical biology revealed by direct NMR Metabonomics Research DayUniversity of Buffalo AmherstMorning Session
Session 1: Scientific Infrastructure for Metabonomics – Instrumentation, Software and Databases Dinesh Sukumaran, Ph.D. Director, Magnetic Resonance Center Department of Chemistry, U. Buffalo Session 3: Metabonomics – Related Research Session 2: Synergy of NMR Spectroscopy and Mass Spectrometry in Metabonomics Prof. Thomas Szyperski Dept. of Chemistry and Biochemistry U. Buffalo Session 4: Metabonomics in an ‘ohmics’ world Prof. George DeTitta Dept. Structural Biology U. Buffalo Prof. Jeremy Nicholson Dept. of Biological Chemistry Imperial College Metabonomics Research DayUniversity of Buffalo AmherstAfternoon Roundtable
TriMR Regional MeetingResearch Triangle ParkFeb. 15, 2007 • Hosted at GlaxoSmithKline Vs.
One-Minute NMR:Integrated System Approach Well Plate or Vial Tray Sample Return 6- or 12-Tray Capacity for Vials or Trays Discovery Tower Web-based Software CapNMR Probe 5- or 10-µL On-Board Instrument Server Multi-Solvent Wash Station Well Plate or Vial Sample Format Accident-Free Syringe and Needle • Microliter precision • 0.1 mm xyz positioning
Automation: Accident-Free Syringe and Needle Carriage comes to rest before needle is lowered
Automation: Solvent Conditioner Solvent Conditioner Vacuum Pump Solvent Bottles Under Positive Pressure Result: Dry, Degassed, Protected Deuterated Solvent
Integrated Approach