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Explore low-cost interventions for drug demand reduction and treatment by leveraging biological markers and targeted pharmacological agents. Learn about prevention strategies and evidence-based treatments.
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An example of low-cost, simple interventions in drug demand reduction Gilberto Gerra Drug Prevention and Health Branch Division for Operations
Do youbelieveinpreventionofdruguseand treatment ofdrugdependence? Complex, confused, unrealistic, fantasy-based, ineffective…
Prevention of cardiovascular diseases – Poker of Aces • No smoking • No salt • No cholesterol • Physical exercise
Addict Biol. 2003 Jun;8(2):123-39. Biological markers of cocaine addiction: implications for medications development. Elkashef and Vocci, 2003 poor understanding of the underlying biology both in the premorbid condition and following the disease state of chronic cocaine use population heterogeneity specific biological changes/markers that could be used to characterize subgroups among chronic cocaine users targeting specific pharmacological agents to subgroups of patients
Seroronin agonists (fluoxetine, citalopram) Serotonin/noradrenaline agonists (venlafaxine-duloxetine) Dopamine agonists/antagonists (modafinil, methylphenidate) NMDA antagonists (memantine, dizocilpine…) Disulfiram GABA-b agonists (baclofen) Kappa-receptor antagonists (buprenorphine + naltrexone) Vaccine