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personal genetics education project. Method to test for certain genetic traits in an embryo Embryo is created via in vitro fertilization Genetic testing occurs when embryo is 2-4 days old, typically at the 8-cell stage A single cell is removed and tested
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personal genetics educationproject • Method to test for certain genetic traits in an embryo • Embryo is created via in vitro fertilization • Genetic testing occurs when embryo is 2-4 days old, typically at the 8-cell stage • A single cell is removed and tested • Results of testing are used to decide which embryos to implant in prospective mother’s uterus What is preimplantation genetic diagnosis?
personal genetics educationproject PGD being performed on a 3-day old embryo Image via http://www.obgyn.net/Frontiers_In_Reproductive_Medicine/images/PGD.gif
personal genetics educationproject Real Families impacted by PGD: Molly and Adam Nash and the Hashmis http://news.bbc.co.uk/olmedia/955000/images/_955928_nash150.jpg http://www.telegraph.co.uk/news/graphics/2007/08/01/nivf101.jpg
personal genetics educationproject Fanconi’s allele Unaffected (carrier) Unaffected (carrier) Non-Fanconi’s allele How is Fanconi’s anemia inherited? Affected Unaffected (carrier) Unaffected (carrier) Unaffected (non carrier)
personal genetics educationproject What are the most common uses of PGD?
personal genetics educationproject Public attitudes on acceptable uses of PGD: