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In The Nam of God. Role of Mammography and breast ultrasound in diagnosis early breast cancer. Dr. Mehri Sirous. * IMAGING *. The standard techniques used for breast imaging are: Screen film x-Ray mammography. Real-Time ultrasound. Other new techniques include:. MRI Color Doppler
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Role of Mammography and breast ultrasound in diagnosis early breast cancer Dr. Mehri Sirous
* IMAGING * • The standard techniques used for breast imaging are: • Screen film x-Ray mammography. • Real-Time ultrasound. • Other new techniques include:
MRI • Color Doppler • Contrast ultrasound • Digital Mammography • Scintimammography
Mammography • Although mammography is the most sensitive exam available for detecting small breast ca. False Negative Rate is 5-10%
False negative rate ↓ * Clinical history and examination * Combination imaging • Mammography standard views • supplementary mammographic views • Local compression views • magnification views • ultrasound * Needle biopsy * F.N.A.C * Or core biopsy
Indications for mammography • Screening asymptomatic women aged 50 years and over • Screening asymptomatic women aged 35 years and over who have a high risk of developing breast cancer: -women who have one or more first degree relatives who have been diagnosed with premenopausal breast cancer - women with histologic risk factors found at previous surgery, e.g. atypical ductal hyperplasia • Investigation of symptomatic women aged 35 years and over with a breast lump or other clinical evidence of breast cancer • Surveillance of the breast following local excision of breast carcinoma . • Evaluation of a breast lump in women following augmentation mammoplasty • Investigation of a suspicious breast lump in a man
Breast ultrasound • At the minimum, a 7.5 MHZ linear array probe should be used • The original role of breast sonography is in the differentiation of cystic and solid lesions • The role of ultrasound complements both clinical examination and mammography • Ultrasound plays an important role in the triple assessment of symptomatic lesions the dense breast
It is the examination of choice in young women and is valuable in the assessment of mammography ‘ dense’ breast
The dense breast • Diffuse increase in the density of the breast tissue is caused by • an increase in the glandular tissue and or/fibrous tissue
The dense breast 2 – edematous breast • Advanced primary tumor • Lymphatic spread from a primary tumor or inflammatory carcinoma • Breast abscess (breast infection) • Congestive cardiac failure and Renal failure (unilateral or bi lateral)
The dense breast • Axillary lymphnode metastases from Advanced gynaecological malignancy e.g ovarian carcinoma, cervical progressively or secondary to a carcinoma of the contra lateral breast • Radiotherapy (breast saving) Develop progressively following radiotherapy Reach a maximum at about 6 months Resolved approximately 18 mouths following treatment
The dense breast • HRT (decrease in the sensitivity of screening mammography for cancer detection) • loss of fat due to severe weight loss or cachexia or lack of fat due to lipodystrophy
Indication of breast ultrasound • .Symptomatic breast lumps in women aged less than 35 years . • Breast lump developing during pregnancy or lactating • .Assessment of mammographic abnormality (further mammographic views) • .Assessment of MRI or scintimammography detected lesions . • Clinical breast mass with negative mammograms . • Breast inflammation • .The augmented breast (together with MRI) • .Breast lump in a male (together with mammography) . • Guidance of needle biopsy or localisation • .Follow-up of breast cancer treated with adjuvant chemotherapy