Susan Regan, PhD Elena Losina, PhD Senica Chetty, MSc Janet Giddy, MBChB, MFamMed

1. Effect of receiving a rapid negative HIV test result on subsequent HIV testing in Durban, South Africa Susan Regan, PhD Elena Losina, PhD Senica Chetty, MSc Janet Giddy, MBChB, MFamMed Rochelle P. Walensky, MD, MPH Jeffrey N. Katz, MD, MSc Kenneth A. Freedberg, MD, MSc Ingrid V. Bassett, MD, MPH Funded by the National Institutes of Health, the Harvard University Center for AIDS Research and the Doris Duke Charitable Foundation

2. # WEPDC203 Objective and Design • Objective: To identify patient characteristics associated with repeat HIV testing after a negative result. • Participants: The South Africa Test Identify and Link (STIAL) cohort • Outpatient departments of 2 hospitals in Durban S.A. • Enrolled immediately before undergoing rapid HIV testing • Have never tested HIV positive before enrollment • Data Collected: • HIV status at enrollment, CD4 count if diagnosed • Self-reported prior testing history, demographics, HIV knowledge, reason for enrollment testing

3. # WEPDC203 Results • 2,915 were enrolled between Aug 2006 and Dec 2008 • 1,691 (55%) were HIV positive at enrollment testing • 17% had previously tested negative for HIV

4. # WEPDC203 Results and Conclusions Multivariate analysis of characteristics associated with prior testing among those HIV negative at enrollment Conclusions • Repeated HIV testing is associated with higher CD4 counts at diagnosis • Women and those with greater knowledge of HIV were more likely to retest • Educational interventions focused on HIV treatment and benefits of regular screening may lead to earlier HIV diagnosis