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State of Clinical HIV Research in Africa

Explore the landscape of clinical HIV research in Africa, from prevention studies to ethical challenges, targeting women and children. Delve into current gaps and major challenges facing researchers in the region. Discover who is involved and the critical work being done to combat the HIV epidemic.

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State of Clinical HIV Research in Africa

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  1. State of Clinical HIV Research in Africa Elly T Katabira, FRCP Department of Medicine Makerere University Medical School Industry and HIV Clinical Research – Focusing on women and children Dakar, Senegal, December 3, 2008

  2. Some of the research being done in Africa • HIV prevention studies • Microbiscides studies • Male circumscion and its impact on female HIV transmission • PMTCT stuudies • HIV intervention studies • Discordant couples studies • Issues on adherence • Variuos clinical trials • For adults and children

  3. Who is doing the research • Indeginous researchers • But poorly funded by local institutions • Collaborative research • Through North-South institutions • Major funding agents • Industries • On a limited scale • Their support through North instuitutions

  4. Major challenges • Poor infrastructure • Inadequate human resources • Research monitoring infrastructure • IRBs, etc. • Ethical issues • How to involve children • Issues of consent among women • Influence on policy makers

  5. Some research gaps • Appropriate interventions for children as they grow up • Impact of adolescence on ART and vice versa • Why PMTCT uptake remains low • Even when it is provided free of charge • Gender issues that influence ART adherence • Both in short term and long term

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