'Induced fit' presentation slideshows

Flexible-Protein Docking

Flexible-Protein Docking. Dr Jonathan Essex School of Chemistry University of Southampton. Southampton. Programme. Existing small-molecule docking Typical approximations, and outcomes Evidence for receptor flexibility, and consequences

1.02k views • 56 slides

Enzymes

542 views • 47 slides

Biochemistry

Biochemistry. Lecture 5. Protein Functions. Binding. +. L. PL. P. Catalysis. Structure. Specificity: Lock-and-Key Model. Proteins typically have high specificity: only certain ligands bind High specificity can be explained by the complementary of the binding site and the ligand.

351 views • 34 slides

ENZYMES

ENZYMES. Definition. Enzymes are protein molecules that catalyze the conversion of one or more substrates into one or more different products enhancing the rate of reaction without affecting equilibrium.

428 views • 31 slides

Specificity of Enzymes

1.66k views • 26 slides

Enzymes

Enzymes. identify the role of enzymes in metabolism, describe their chemical composition and use a simple model to describe their specificity on substrates. What are they?.

452 views • 25 slides

Types of non-covalent interactions

The induced dipole ( d,e ) and the dispersion forces (f) depend on the distortion of the electron distribution in a nonpolar atom or molecule. The symbols q-, q+ denote a fraction of an electron or proton charge (a partial charge ? ). Types of non-covalent interactions.

2.89k views • 24 slides

How to approximate complex physical and thermodynamic interactions?

Automated Molecular Docking Issues. How to approximate complex physical and thermodynamic interactions? Employ rigid or flexible structures for ligand and receptor (Side-chains or Back-bone flexible) How to handle molecular motions? Treat with full atomic detail or simplified models?

364 views • 24 slides

352 views • 21 slides

Principles of Enzyme Catalysis

Principles of Enzyme Catalysis. Thermodynamics is concerned with only the initial and final states of a process, being independent of the path(s) between the two states.

762 views • 21 slides

Hypothesis-Driven Science

Hypothesis-Driven Science. As a formal process of inquiry, the scientific method consists of a series of steps. The key element of the scientific method is hypothesis-driven science. Revise and repeat. Observation. Question. Hypothesis. Prediction. Experiment. Figure UN1-4.

555 views • 21 slides

Enzymes

492 views • 19 slides

Enzymes Part 1

Enzymes Part 1. M.F.Ullah, Ph.D Showket H.Bhat, PhD. COURSE TITLE : BIOCHEMISTRY 1 COURSE CODE : BCHT 201. PLACEMENT/YEAR/LEVEL: 2nd Year/Level 4, 1st Semester. What Are Enzymes?. Enzymes are Proteins Act as Catalyst to accelerates a reaction

374 views • 17 slides

Enzymes

Enzymes. Question:. What are enzymes ?. Enzymes. Answer: 1. Proteins: most enzymes are proteins , primarily tertiary and quaternary structures . 2. Catalyst: chemical agent that accelerates a reaction without being permanently changed in the process. Enzymes.

504 views • 16 slides

Neurotoxin

Neurotoxin. Mamba snake. Why Fasciculin ?. Mambas have only Fasciculin Fasciculins : a family of closely related peptides isolated from Mamba venom toxins (FAS-I, FAS-II, and FAS-III)

464 views • 16 slides

The Hindenberg

The Hindenberg. The Crash.

315 views • 16 slides

The Hindenberg

The Hindenberg. The Crash.

171 views • 16 slides

Immunoglobulin Structure II

Immunoglobulin Structure II. Jr. Hons. Immunology B.Sc. D. I. Stott. Immunoglobulin Domain. IgG Domain Structure: Fab & Fc. 3-D Structure of IgG: whole molecule. 3-D Ribbon Model of Mouse IgG 2a. 3-D Model of IgG1. 3-D Model of IgA. 3-D Model of IgM.

495 views • 15 slides

Enzymes

Enzymes. Honors Biology . Objectives. Construct and revise an explanation based on evidence for how carbon, hydrogen, and oxygen from sugar molecules may combine with other elements to form amino acids and/or other large carbon-based molecules .

258 views • 12 slides

Chemical Reaction A chemical change occurs

+. +. A. B. AB. yields. Chemical Reaction A chemical change occurs. +. -or-. +. A. B. AB. yields. Parts of a Chemical Reaction. Reactant Product Lactose Glucose + Galactose Lactose is broken down because a chemical reaction occurs. Enzyme Basics. What is an enzyme?

312 views • 9 slides