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Laser Vibro Cardio Graph

Laser Vibro Cardio Graph. Non contact, distance, high resolution displacement measurement for Cardiac, Vascular and Respiratory measurement related to vessel compliance, pulse velocity and vessel impedence changes, heart beat and respiration rithm. Application examples:

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Laser Vibro Cardio Graph

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  1. Laser Vibro Cardio Graph Non contact, distance, high resolution displacement measurement for Cardiac, Vascular and Respiratory measurement related to vessel compliance, pulse velocity and vessel impedence changes, heart beat and respiration rithm • Application examples: • Burnt patient monitoring (no electrodes on skin) • Ventricular Synchronization without Echographic guide; Sudden dead in Children Monitoring • MRI cardiac monitoring, Survey in pharmacy • Vascular disease and Cardiac surgery weaning Simpato-vagal balance (ARMA spectra and fractal dimensions identification VCG ECG Future development: economic device from industrial engineering to put the technology on the health market Collaboration : Crisel Instrument Ospedale Bambino Gesù - Rome International Patent by researchers of ISS - Università Politecnica delle Marche – Politecnico di Torino 1

  2. Cardiovascular bioengineering unit: • Research areas: • Biomedical signal processing of ECG, intracardiac signal, body surface potential map, heart rate variability, gene expression data • Telemedicine solutions: design, realization, prototyping and assessment • Electromagnetic interference on medical devices: wireless communication technology and/or MRI versus active implantable devices (pacemakers, neurostimulators, etc…) and life-support devices • Pathologies: • Heart failure • Atrial fibrillation • Bradiarrhytmias, tachiarrhythmias 2

  3. Cardiovascular bioengineering unit: Laboratory facilities and instrumentation Biomedical signal acquisition and processing: • Biosemi (multichannel biopotential acquisition system, for research use only) • Biopack (MRI compliant acquisition system, for research use only) • Portapress (non-invasive continous blood pressure monitoring) • Matlab SW • Labview SW Electronic workshop: • Printed circuits design and realization • Microcontroller IDE SW • Altium SW Electromagnetic compatibility laboratory: • Anechoic chamber (with associated instrumentations) • MRI RF coil (with associated instrumentations) • Luxtron Fluoroptic temperature probes 3

  4. Innovative devices for Neuro-rehabilitation Design and fabrication of large-area, ultra-flexible, active grids for recording and stimulation on the cortical surface. Moderately invasive, chronically implantable device for improving rehabilitation through stimulation Planned design Prototype: Kapton thin grid; piezo motors for concurrent depth electrodes penetration ISS PI film with polysilicon TFTs IMM-CNR Collaboration: Prof. YosiShacham Faculty of Engineering Tel Aviv 4

  5. Needed: understanding the effect of direct stimulation in complex networks of neurons Collaboration: Prof. Shimon MaromTechnion, Haifa Marom Patterned substrate for growing modular networks of cortical neurons in-vitro Cortical neurons cultured on microarrays and superposed spikes from a single neuron. Theory: inferring the stimulated remote site from the spectral analysis of local activity ISS 5

  6. Molecular imaging with radionuclides • Compact, dual head, scintimammograph • Early detection of breast cancer • Optimized for breast compression and dual modal • International patent pending • Open, multi-heads SPECT system • Application examples: • Therapeutic effectiveness of stem cell in stroke induced heart disease • Atherosclerotic plaques identification Dedicated electronics with independent channel readout and smart real time processing • Future development: • Improve coregistration of the heads images • Optimize exploitation of the electronics features 6

  7. SNIFFER: Aerial platform for nuclear emergency and environmental monitoring • Applications: • Support radiological emergency • Radiological surveillance on large scale • Mapping of radioactive contamination on ground • Atmospheric pollution monitoring ISTISAN report: 07/33 Web: http://www.iss.infn.it/webg3/g3iss/aereo/ • SNIFFER Components • Compact aerial platform • Isokinetic sampling system for quantitative particulate radioactivity measurements • Nuclear detectors for radioactivity contamination measurements on ground and in atmosphere, with gamma-radioisotopes identification • VOC-PAH sampling unit for measurements of organic pollutants • Management, control and acquisition system, including environmental sensors and geolocation devices • Future development: • Real-time air-ground data communication • Migrate on an unmanned aerial platform • Improve nuclear detectors 7

  8. VISION and OPHTHALMOLOGY The Department is active, from many years, in this research field. Retina is the focal point, due to the growing incidence and social impact of macular degenerations on a aging population. Innovative methods are developed in our labs and applied in physiological and clinical studies, to improve knowledge of retinal function and assess new therapeutic approaches. Our focal ERG system is equipped with a special electronics, needed to evaluate extremely low-level responses, as occurs in clinical trials involving patients with advanced AMD An experimental LDF apparatus (Laser Doppler Flowmetry) is under development. Includes multispectral light stimulation to study retinal neurovascular coupling In collaboration with: - Benedetto Falsini, Catholic University, Rome - Eyal Banin, Hadassah Hospital, Jerusalem - Charles Riva, Institute of Research in Ophthalmology, Sion - Vittorio Porciatti, Bascom Palmer Eye Institute, Miami 8

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