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DNA. RNA. Translation. Transcription. Gene regulations. Mutation. Viral Structure and Replication. Technology. Disorders. Nondisjunction- when the chromosomes don’t split from each other giving one cell more than the other.
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Disorders • Nondisjunction- when the chromosomes don’t split from each other giving one cell more than the other. • Autosomal- these are all of your chromosomes except for your sex chromosomes. You have 44 autosomal chromosomes. • Down syndrome- produces mild to severe mental retardation. (nondisjunction) • Albinism- lack of pigment (recessive) • Cystic fibrosis- excess mucus in lungs, digestive tract, liver; increased susceptibility to infections (recessive) • Galactosemia- accumulation of galactose (sugar) in tissue, mental retardation; eye and liver damage (recessive)
Phenylketonuria PKU- accumulation of phenylalanine in tissue; lack of normal skin pigment; mental retardation (recessive) • Tay-Sachs disease- lipids accumulation in brain cells; mental deficiency; blindness; death in early childhood (recessive) • Achondroplasia- Dwarfism (dominant) • Hunington’s disease- mental deterioration and uncontrolled movements (dominant) • Hypercholesterolemia- excess cholesterol in blood; heart disease (dominant) • Sickle cell- misshapen, or sickled, red blood cells; damage to many tissue (co-dominant)