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Principales phases du cycle de multiplication virale

Principales phases du cycle de multiplication virale. Virus libre. Fusion. 1 - Fixation : Gp120/CD4 2 - Fusion : Gp41 3 - Pénétration : Entrée de la nucléocapside Libération de 2 ARNv + RT 4 - Transcription inverse : 1 ARNv  ADN db circulaire

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Principales phases du cycle de multiplication virale

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  1. Principales phases du cycle de multiplication virale Virus libre Fusion • 1 - Fixation : Gp120/CD4 • 2 - Fusion : Gp41 • 3 - Pénétration : • Entrée de la nucléocapside • Libération de 2 ARNv + RT • 4 - Transcription inverse : 1 ARNv ADN db circulaire • 5 - Intégration de l’ADNv dans l’ADN cellulaire • 6 - Transcription : synthèse d’ARNv • 7 - Traduction : synthèse des protéines virales • 8 - Assemblage et bourgeonnement • 9 - Lyse de la cellule hôte Adsorption Internalisation CD4 Reverse Transcriptase ARN ADN proviral Intégrase ADNcellulaire ADN non intégré Transcription ARNm Synthèse protéique Réticulum endoplasmiqueAppareil de Golgi ARNv Bourgeonnement Virions matures infectieux Sylvie Bardes – Lycée de la Vallée de Chevreuse – 2005/2006

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