A-Catenin Is a Molecular Switch that Binds E-Cadherin-b-Catenin and Regulates Actin-Filament Assembly

Oct 17, 2012

460 likes | 772 Views

Share Presentation

Embed Code

Link

sheri

Download Presentation

A-Catenin Is a Molecular Switch that Binds E-Cadherin-b-Catenin and Regulates Actin-Filament Assembly

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

Cadherin-Catenin-Actin Complex

Cadherin-Catenin-Actin Complex. Piyush Bajaj BIOE 506 April 29 th , 2008. Cadherins in development:cell adhesion, sorting and tissue morphogenesis Jennifer M. Halbleib and W. James Nelson, Genes and Development , 2006. Summary

775 views • 27 slides

Speech that FDA Regulates

Speech that FDA Regulates. William A. McConagha Office of Accountability Food & Drug Administration Risk Communication Advisory Committee February 28, 2008. Purpose of Presentation. To give a broad overview of the types of speech that FDA regulates, and

490 views • 23 slides

APC Beta Catenin pathway Belongs to tumor suppressor gene Functions

APC Beta Catenin pathway Belongs to tumor suppressor gene Functions It is a cytoplasmic protein whose dominant function is to regulate the intracellular levels of β- catenin , a protein with many functions. Down regulation of growth promoting signals.

980 views • 73 slides

b -actin

Supplemental Figure. A. B. Ectopic. Ectopic. Dienogest. Dienogest. Eutopic. Eutopic. Control. Control. LA. LA. ER a. PR-B. ER b. Total-PR. b -actin. b -actin.

150 views • 1 slides

Total b -catenin

Supplementary Figure 1. Band Intensity. Total b -catenin. Active b -catenin. c- myc SOX-9 GSK-3 b tubulin. Supplementary Figure 2. A. C. Activity at 90min. Activity. B. a -GFP. ALDOA ALDOB ALDOC.

168 views • 2 slides

β-Catenin, Cancer, and G Proteins Not Just for Frizzleds Anymore

β-Catenin, Cancer, and G Proteins Not Just for Frizzleds Anymore. Ming Yang et al. PNAS . 2005. Maria Domenica Castellone et al . Science . 2005. G-protein signal pathways and subfamilies. Ligand. a s, a olf. a i1, a i2, a i3, a oa,

238 views • 16 slides

Regulation of the Wnt/ b -catenin pathway by redox signaling.

Regulation of the Wnt/ b -catenin pathway by redox signaling. Funato Y. et al. Nat Cell Biol . 8(5):501-8. (2006). NEDL-1. Miyazaki K. et al. J Biol Chem. 279(12):11327-11335. (2004). Inversin. Simons M. et al. Nat Genet . 37(5):537-543. (2005). KLHL12-Cullin-3.

358 views • 16 slides

b -catenin signaling during early Xenopus development

b -catenin signaling during early Xenopus development.

108 views • 2 slides

A/B Switch between VFO A & B

A. B. C. D. A/B Switch between VFO A & B. A=B Hold for .5 sec to copy A to B. SPL Press to activate split freq..... operation. QMB Recall QMB frequencies. V>M Hold for .5 sec to tfr VFO to Mem. RPT Applies offset to display freq. REV Reverses input / output freqs. M>V

186 views • 2 slides

E cadherin and Metastasis

E cadherin and Metastasis. By Andy Ciesielski. CDH1 gene. Encodes E Cadherin 16q22.1 Ca2+ Dependent Cell-Cell Adhesion Molecule 16 exons.

522 views • 14 slides

Smad7-induced b -catenin degradation alters epidermal appendage development

Smad7-induced b -catenin degradation alters epidermal appendage development. Han, G. et al., 2006, Dev Cell. Diagrammatic Depiction of the Hair Follicle Stem Cell Niche and the Cutaneous Lineages Deriving from the Bulge Stem Cells Adapted from Alonso and Fuchs, 2003.

289 views • 21 slides

OCLC is a BIG SWITCH

OCLC is a BIG SWITCH. 60,457 libraries in 112 countries AMICAL is catching OCLC. 1,148. 5,697. 48,535. 4,204. 100 million records Almost 1 million from AMICAL 1.2 billion location symbols. 873. A VERY BUSY SWITCH. China, Germany, British Library, Brazil, AMICAL.

306 views • 13 slides

W B E A / O B E A

W B E A / O B E A. Portland, Oregon February 13 – 17, 2014. DoubleTree by Hilton. It starts with a warm chocolate chip cookie to welcome you. Portland Weather in February. 10 Miles 16 minutes From Portland Airport to DoubleTree Hotel Taxi  MAX  Rental Car.

634 views • 49 slides

Cadherin- -catenin Adhesion Complexes in Synaptic Development and Remodeling

Cadherin- -catenin Adhesion Complexes in Synaptic Development and Remodeling. Shernaz X. Bamji University of British Columbia 2006 NIDA Frontiers in Addiction Mini-Convention. Cadherin Superfamily. P. P. -cat. -cat. F-actin. Type II: VE-cad K-cad cad-8 to 12 cad-18 to 20 cad-24.

327 views • 19 slides

b -Catenin IP - Myc Promoter

A. B. b -Catenin IP - Myc Promoter. b -Catenin IP - Cyclin D1 Promoter. 30. 25. 25. 20. 20. % Input. 15. % Input. 15. 10. 10. 5. 5. 0. 0. Control. DHT. Wnt3A. Control. DHT. Wnt3A. C. D. AR IP - Myc Promoter. AR IP - Cyclin D1 Promoter. 30. 40. 35. 25. 30. 20. 25.

88 views • 1 slides

mRNA expression (/ b -actin )

Supplemental fig . 5 Fibroblast-related and PDL-related gene expression and collagen expression in Activin A-treated in HPDLC-3O and -3Q. (B). **. **. **. **. mRNA expression (/ b -actin ). mRNA expression (/ b -actin ). mRNA expression (/ b -actin ). **. **. **. **.

112 views • 1 slides

Actin Filament Assembly, Growth, Branching, Capping and Disassembly are

Actin Filament Assembly, Growth, Branching, Capping and Disassembly are Controlled by Actin Binding Proteins. Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes Matthew D. Welch et al.

443 views • 23 slides

Transgenic β-catenin

A. NT Wt-1 Wt-2 Mut-1 Mut-2 Mut-3. Transgenic β-catenin. GAPDH. B. Mut-1 NT Mut-2 NT C N C N C N C N. Total β-catenin. HSP90.

129 views • 1 slides

Wnt/β-catenin pathway

Wnt/β-catenin pathway. Seminar Spring 2011 Maneeshi Prasad 21st Jan 2011 Man. Wnt pathway. Ligands Receptors Intracellular components Transcription factors Interactome. Wnt. “Wnt” is a combination of Wg (wingless) gene in Drosophila and Int gene in MMTV, two homologous genes

405 views • 13 slides

BAFF/ b -actin

A. B. BAFF/ b -actin. BAFF/ b -actin. D. C. Group C (3MU LE-IFN a ). Group B (1MU LE-IFN a ). Group A (Placebo ). CXCL-10/ b -actin. CXCL-10/ b -actin. *. *. *. *. *. *. *. *. *. *. *. *. *. *. *. *. *. *. F. E. MxA/ b -actin. MxA/ b -actin. T0. T2. T42. T44.

158 views • 1 slides

The Tie That Binds

The Tie That Binds. Barb Williams Elaine Hoffert. The Tie That Binds: Reading, Writing, and Assessment. Goals. To identify for all courses the connections among Standards Texts Strategies Assessments (Writing). Clear Target.

709 views • 54 slides

Aberrant Wnt / b -catenin signaling can induce

Aberrant Wnt / b -catenin signaling can induce. chromosomal instability in colon cancer. Behrens. J et al , PNAS, 2006. Introduction. ◦ The hallmarks of colon tumors. - APC mutation. Mutations in APC are the most frequent events in colon tumors. (Powell, S.M et al , Nature , 1992).

243 views • 12 slides

More Related

A-Catenin Is a Molecular Switch that Binds E-Cadherin-b-Catenin and Regulates Actin-Filament Assembly

A-Catenin Is a Molecular Switch that Binds E-Cadherin-b-Catenin and Regulates Actin-Filament Assembly

Presentation Transcript

Cadherin-Catenin-Actin Complex

Speech that FDA Regulates

APC Beta Catenin pathway Belongs to tumor suppressor gene Functions

b -actin

Total b -catenin

β-Catenin, Cancer, and G Proteins Not Just for Frizzleds Anymore

Regulation of the Wnt/ b -catenin pathway by redox signaling.

b -catenin signaling during early Xenopus development

A/B Switch between VFO A &amp; B

E cadherin and Metastasis

Smad7-induced b -catenin degradation alters epidermal appendage development

OCLC is a BIG SWITCH

W B E A / O B E A

Cadherin- -catenin Adhesion Complexes in Synaptic Development and Remodeling

b -Catenin IP - Myc Promoter

mRNA expression (/ b -actin )

Actin Filament Assembly, Growth, Branching, Capping and Disassembly are

Transgenic β-catenin

Wnt/β-catenin pathway

BAFF/ b -actin

The Tie That Binds

Aberrant Wnt / b -catenin signaling can induce

A/B Switch between VFO A & B