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JRC Activities on Endocrine Disrupters | Supporting EU Policies with Independent Evidence

Explore the Joint Research Centre's mission to support EU policies with independent evidence on endocrine disrupters. Learn about testing strategies, validation approaches, stakeholder dialogue, and more.

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JRC Activities on Endocrine Disrupters | Supporting EU Policies with Independent Evidence

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  1. JRC support to EC work on endocrine disrupters Elise Grignard 23 November 2018

  2. Joint Research Centre's Mission " As the science and knowledge service of the Commission our mission is to support EU policies with independent evidence throughout the whole policy cycle "

  3. EURL ECVAM Established under Directive 2010/63/EU on the protection of animals used for scientific purposes • Integrating testing strategies/developing new risk assessment paradigms (avoiding use of animals) • Validation of testing approaches • Dissemination and application: • Facilitating stakeholder dialogue • International promotion and regulatory acceptance (e.g.OECD)

  4. JRC Activities on Endocrine Disrupters • Scientific criteria for the identification of endocrine disrupting substances

  5. Priorities for new testing approaches • Workshop on setting priorities for further development and validation of test methods and testing approaches for evaluating endocrine disruptors – May 2017 • https://publications.europa.eu/en/publication-detail/-/publication/6b464845-4833-11e8-be1d-01aa75ed71a1/language-en/format-PDF/source-search • Draft Detailed Review Paper on the retinoid system • Workshop on thyroid disruption – March 2017 • https://publications.europa.eu/en/publication-detail/-/publication/472d2c88-a8b1-11e7-837e-01aa75ed71a1/language-en/format-PDF/source-search • Temporal aspects in the testing of chemicals for endocrine disrupting effects (in relation to human health and the environment) – Jan 2018 • https://publications.europa.eu/en/publication-detail/-/publication/58430e34-f4ef-11e7-be11-01aa75ed71a1/language-en https://publications.europa.eu/en/publication-detail/-/publication/1c678970-3aad-11e7-a08e-01aa75ed71a1/language-en/format-PDF/source-search

  6. Priorities for new testing approaches • Development of a study protocol for thyroid disruptor testing in the mammalian system • Horizon 2020 -

  7. EU NETVAL Validation Study • EURL ECVAM: validation study to assess in vitro methods for the detection of thyroid disrupters • 17 methods investigated by 14 laboratories of the EU-NETVAL (European Union Network of Laboratories for the Validation of Alternative Methods) https://ec.europa.eu/jrc/en/science-update/vitro-methods-detection-thyroid-disruptors

  8. JRC Activities on Endocrine Disrupters

  9. EURL ECVAM Status report - 2018 coming soon

  10. Any questions? You can find me elise.grignard@ec.europa.eu

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