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Matthew Mancuso BEE 7600, Professor Dan Luo

Nucleic Acids & Nanoparticles in the Luo Lab. Matthew Mancuso BEE 7600, Professor Dan Luo Department of Biomedical Engineering, Cornell University Presented Thursday March 31 st , 2011. Points to Cover. 1.) Patterning by Controlled Evaporation.

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Matthew Mancuso BEE 7600, Professor Dan Luo

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  1. Nucleic Acids & Nanoparticlesin the Luo Lab Matthew Mancuso BEE 7600, Professor Dan Luo Department of Biomedical Engineering, Cornell University Presented Thursday March 31st, 2011

  2. Points to Cover • 1.) Patterning by Controlled Evaporation • 2.) Free-Standing Nanoparticle Superlattices 3.) Nanocrystal Characterization

  3. DNA-Nanoparticle Structures: Different Crystals • 1.) So what’s the big deal with DNA? How does it help us make nanostructures when combined with Goldnanoparticles? C. A. Mirkin, R. L. Letsinger, R. C. Mucic, and J. J. Storhoff, "A DNA-based method for assembling nanoparticles into macroscopic materials," Nature 382, 607-609 (1996) Alivisatos, A. P.; Johnsson, K. P.; Peng, X. G.; Wilson, T. E.; Loweth, C. J.; Bruchez, M. P.; Schultz, P. G., Organization of 'nanocrystal molecules' using DNA. Nature 1996, 382, (6592), 609-611. • The Bottom Line: • Base pair matching allows DNA-NP structures to be highly specific. • GNPs allow for the creation of structures with vastly different material properties. • 1996

  4. Nanopatterning via Microdroplets W.L. Cheng, N.Y. Park, M.T. Walter, M.R. Hartman, D. Luo, Nanopatterning self-assembled nanoparticle superlattices by mouldingmicrodroplets, Nature Nanotechnology 3 (2008) 682-690.

  5. Nanopatterning via microdroplets W.L. Cheng, N.Y. Park, M.T. Walter, M.R. Hartman, D. Luo, Nanopatterning self-assembled nanoparticle superlattices by mouldingmicrodroplets, Nature Nanotechnology 3 (2008) 682-690.

  6. Free-Standing Nanoparticle Superlattices W.L. Cheng, M.J. Campolongo, J.J. Cha, S.J. Tan, C.C. Umbach, D.A. Muller, D. Luo, Free-standing nanoparticle superlattice sheets controlled by DNA, Nature Materials 8 (2009) 519-525. W.L. Cheng, M.J. Campolongo, S.J. Tan, D. Luo, Freestanding ultrathin nano-membranes via self assembly, Nano Today 4 (2009) 482-493.

  7. Free-Standing Ultra-thin Nanoparticle MembranesFUN! Membranes W.L. Cheng, M.J. Campolongo, J.J. Cha, S.J. Tan, C.C. Umbach, D.A. Muller, D. Luo, Free-standing nanoparticle superlattice sheets controlled by DNA, Nature Materials 8 (2009) 519-525. W.L. Cheng, M.J. Campolongo, S.J. Tan, D. Luo, Freestanding ultrathin nano-membranes via self assembly, Nano Today 4 (2009) 482-493.

  8. Other FUN Membranes 30,000 Smaller! 70,000 Heavier! R. Vendamme, S.-Y. Onoue, A. Nakao and T. Kunitake, Nat. Mater.5 (2006)

  9. FUN Membranes

  10. DNA-Capped Nanoparticle Assembly

  11. Free-Standing Nanoparticle Superlattices

  12. Free-Standing Nanoparticle Superlattices

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