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Learn about the diagnosis, treatment, and management of heart failure to effectively save failing hearts. Understand the risk factors, symptoms, diagnostic tests, and medications involved. Available in text language.
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How to Save the Failing Heart Subir Shah Assistant Professor in Cardiology
Definition • Intern answer: Someone short of breath with fluid all over • Guideline answer: A Disease process that results from any structural or functional impairment of ventricular filling or ejection of blood
Distinction of Kinds of HF • HFpEF= Heart Failure with a preserved ejection fraction. EF >50% • HFrEF= Heart Failure with a reduced ejection fraction. EF<40% • What about 41%-49%
Diagnosing it • Intern answer: CXR, BNP, BMP, Echo, ask the nurse what they think, call my senior resident • Guideline answer: There is no single diagnostic test for HF because it is largely a clinical diagnosis based on a careful history and physical exam • So…..
Stepwise Approach • Who gets it • History • Physical • Labs • Therapy • Breathe…. • Documentation • Sign it out and get the heck out of the hospital
Who gets it: Epidemiology • Pts above age 40 have a 20% chance of developing HF • so you have a 20% chance of making the right diagnosis • African American men have the highest prevalence • Easier: Pt’s with a HF dx and a recent admission of CHF • CHF has a 25% readmission rate nationwide in the first 30 days
Who gets it: HF risk factors • HTN (50% of pts admitted with HF have BP>140/90 • DM • Atherosclerotic Disease • Metabolic Syndrome • 3 of the following (abdominal adiposity, hypertriglyceridemia, low HDL, HTN, DM) • OSA • Medication noncompliance or Decreased Effect
Subgroups of HF • Pts with ACS • Pts with Accelerated HTN • Pts with Acute decompensated HF • Pts with Shock • Pts with acutely worsening right HF • Pts after surgery
Common Factors that precipitate Acute Decompensated HF • Non adherence to meds, sodium (<2 grams), or fluid restriction (<1.5-2 Liters) 1L=32 oz • Acute Myocardial Ischemia • Uncorrected HTN • Recent addition of negative inotropes (verapamil, diltiazem, Beta Blockers) • PE • Initiation of drugs that increase salt retention • Steroids, NSAIDS, TZDS • Excessive alcohol or drug use • Concurrent infections • Endocrine abnormalities (hyper,hypothyroid, DM)
How to Diagnose it.. All about the HISTORY!!! • LETS FIGURE THESE OUT AS A GROUP
History • Anorexia, early satiety, weight loss • GI sx common in CHF • Rapid weight gain (suggests volume overload) • Palpitations, syncope, AICD shocks • Could be indicative of A fib or Vtach • Peripheral edema ascites • PND, orthopnea • Hx prior hospitalizations or frequent hospitalizations • Diet (high sodium diet) • Adherence to medications
Physical • Obesity or cardiac cachexia • Blood pressure (HTN or hypotension in HF) • Width of pulse pressure would make u consider decreased cardiac output • JVP at rest and following abdominal compression • Most useful finding on PE to identify congestion • Extra heart sounds (S3 assoc with adverse prognosis in HFrEF) • Hepatomegaly and ascites • Peripheral edema • Temperature of lower extremities (cool lower extremities mean decreased cardiac output)
Labs/Tests • BNP (Class Ia) to help establish dx of AECHF • Class IIB level C to guide therapy • Troponin(increase is assoc with worse prognosis) • CXR (Class I C) – to assess heart size and pulmonary congestion • EKG (view arrhythmias and chamber size) • Echo, RHC, and LHC
BNP elevation causes • CARDIAC • CHF • LVH • ACS • Pericardial dz • Valvular dz • A fib • Cardioversion • Myocarditis • NON-CARDIAC • Advancing Age • Anemia • Pulmonary HTN • Severe PNA • Critical Illness • Bacterial Sepsis • Severe Burns • Chemotherapy
Diuretics • Lasix • Initial daily dose: 20 to 40 mg qd or bid • Maximum daily dose: 600 mg • Duration of action 6-8 hrs • Bumex • Initial Daily dose: 0.5mg -1 mg qday or bid • Maximum daily dose: 10 mg • Duration of action: 4-6 hours • Metolazoneand Diuril
Risks of Diuretics • Electrolyte and Fluid Depletion • Hypotension • Azotemia • Senior yelling at you
Intravenous Inotropic Agents • Adrenergic Agonists: CO and HR • Dopamine… initial dose 5-10 mcg/kg/min • Dobutamine… initial dose 2.5-5 mcg/kg/min • PDE Inhibitors: CO and HR • Milrinone 0.125-.75 mcg/kg/min
What about the maintenance meds? • Class 1 Indications • Pts on GDMT can be kept on it in acute exacerbations if thermodynamically stable • Starting a BB is recommended AFTER optimization of volume status and successful discontinuation of Intravenous diuretics, vasodilators, and inotropic agents. • BB should be started at low dose and only in stable pts. Caution when a pt was on inotropes
Documentation • Take credit IN THE CHART • Describe Reasoning for treating the way you treated and describe if they responded • Proper Term: Acute on Chronic systolic/diastolic Heart failure • HFrEF and HFpEF is ALLOWED
Initial Follow-Up • Actually follow up and see the patient • Recheck vitals • Strict I’s and O’s- may need catheter • Place them on the RIGHT amt of Oxygen • Bipap if necessary • Code status discussion • Sign it out