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Anatomy Review

Explore bacterial systemic diseases affecting the cardiovascular system, including septicemias, plague, tularemia, and Lyme disease. Learn about transmission, symptoms, and treatment options for these potentially lethal conditions.

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Anatomy Review

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  1. Anatomy Review • Heart • Blood Vessels • Blood

  2. Cardiovascular and Lymphatic Disease — Bacterial Septicemias • Septicemia • Lymphangitis • Commonly Gram –ve • Septic shock may be lethal • 50-70% death rate

  3. BacterialCardiovascular and Lymphatic Disease • Puerperal Fever (Childbirth fever) • ________________________ • Poor asepsis after childbirth or abortion • Microbes enter uterus • Penicillin usually effective, slow recovery • Group B Streptococcal Disease • _________________________ • Neonatal sepsis/ meningitis • Common in vaginal microflora, testing is recommended in 3rd trimester

  4. Bacterial Systemic Disease — Plague • Yersinia pestis • ______________ – chipmunk borne in U.S.A. • __________________ – rat borne • Highly virulent • Phagocyte destruction • Complement degradation • Multiple entry routes • 50- 60% mortality

  5. Plague Types • ________________ • Blackish hemorrhages seen through skin • Grossly swollen lymph nodes • Antibiotics will cure, if Dx is prompt • _________________ • Microbes in blood • Meningitis, pneumonia, death • _________________ • Invariably fatal in 1-3 days • Medical workers at risk • Delta 32 CCR5 mutation

  6. Bacterial Systemic Disease — Tularemia • Francisella tularensis • Rodent borne (esp. cotton tail rabbits) • Multiple entry routes • Symptoms • Microbes multiply in phagocytic cells • Antibiotics are effective

  7. Bacterial Systemic Disease — Lyme Disease • Borrhelia burgdorferi • Tick borne • Flu-like symptoms • Bull’s eye rash • Treatable with _____________ • Failure to treat

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