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Experiences and Disorders of the Gynecologic Client Physiology of Puberty, Menarche and Fertility. Marianne F. Moore RN, MSN, CNM. Physiology of Puberty. Puberty refers to the period of sexual maturation.
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Experiences and Disorders of the Gynecologic ClientPhysiology of Puberty, Menarche and Fertility Marianne F. Moore RN, MSN, CNM
Physiology of Puberty • Puberty refers to the period of sexual maturation. • Puberty is when the child experiences physical, hormonal, and sexual changes and becomes capable of reproduction. • Associated with rapid growth and the appearance of secondary sexual characteristics.
Physiology of Puberty • Changes triggered by hypothalamus and pituitary gland • Ovaries begin to produce estrogen and progesterone • Adolescence is the period of transition between puberty and adulthood.
Physiology of Puberty Before menarche, girls experience • rapid growth, especially an increase in height • breast enlargement • pubic, armpit, and leg hair growth • clear or whitish vaginal secretions • increased hip width
Physiology of Menarche Menarche refers to the starts of the menstrual cycle Occurs between age 9-16 in girls Initial cycles are often anovulatory Irregularity is normal As ovulation established, cycles regulate
Physiology of Menses Follicular Phase • Hypothalamus/GnRH stimulates anterior pituitary to make FSH/LH • FSH causes granulosa cells to make estadiol and follicles are recruited • One follicle dominates and it has the most FSH receptors
Physiology of Menses Follicular Phase • The follicle produces inhibin, and FSH is suppressed • Loss of FSH causes smaller follicles to die off. The dominant follicle grows. • LH causes stromal cells to make androgens close to ovulation-increases sexual desire.
Physiology of Menses Ovulatory phase • Peaking estradiol levels cause a surge of LH and FSH • LH causes resumption of meiosis, luteinization of granulosa cells and progesterone production • 10-12 hours later, the follicular wall breaks down and ovulation occurs
Physiology of Menses Luteal phase • Granulosa and theca cells take up steroids and lutein; corpus luteum. • Progesterone dominated phase • Progesterone suppresses new follicles • Causes secretory changes in the endometrium that support implantation
Physiology of Menses Luteal phase • Progesterone peaks 7-8 days after LH surge; at implantation if it occurs • Luteal phase more constant than follicular phase-14 days if no pregnancy • Progesterone causes the elevation in basal body temperature (BBT) • BBT rise confirms ovulation
Physiology of Menses Menstrual phase • At 9-11 days after ovulation, corpus luteum declines • Progesterone/ estrogen levels decline. • Withdrawal shrinks endometrium, decreases blood flow, and begins pulsatile dilation/constriction of spiral arterioles • Ischemia and stasis alternate with hemorrhage, and menstrual flow begins
Physiology of Menses Menstrual phase • Normal blood loss w/menses 20-80 ml • 70% sloughs by second day • 90% by third day • Average length of menses 4-6 days • Rising estrogen levels by day 5 and thrombin plugs limit blood loss
Physiology of Fertility Female • Estrogen softens cervix and thins mucous; helps sperm to enter uterus • Androgen surge with ovulation increases desire • Oocyte can be fertilized for 12-24 hours after ovulation • Sperm viable in the upper genital tract for up to 72 hours
Physiology of Fertility Female • Cervical mucous favors passage of normal sperm • Improves overall quality of sperm meeting egg • Fertilization occurs in ampullary region of the tube • Fimbria sweep conceptus into uterus • Implantation begins at the blastocyst stage
Physiology of Fertility Male • Male deposits as many as 300 million sperm near cervix with intercourse • Sperm must be normal in shape, adequate in amount and have motility to ascend the genital tract
Physiology of Fertility Male • Some sperm pass through entire tract rapidly; others sit in cervical crypts and ascend later • Sperm are made continuously • Abnormalities can be related to infections, varicoceles, overall health
Cultural considerations • Value of women and children • Role of women in the home and in the world • Menstrual flow as “dirty”
Lifestyle considerations • Personal values • Family needs • Sexual preferences • Personal comfort with own body
Trends in nursing research • Recent research concerns PMS, PMDD and symptom management for menstrual disorders • The Seattle Midlife Women’s Health Study (SMWHS) studied the natural menopausal transition in a population-based sample from 1990 to 2006. • The primary focus of SMWHS throughout the 17 years was on symptoms, hormones, stress and stages of the menopausal transition. • 390 women initially, 176 at end of study