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Building High-Quality Guidelines With BRIDGE-Wiz E-GAPPS at NYAM

Building High-Quality Guidelines With BRIDGE-Wiz E-GAPPS at NYAM. Richard N. Shiffman, MD, MCIS Yale School of Medicine. Overview. Essential background Rationale: Why software? Ideal recommendation Action-types Level of obligation Building a recommendation. Rationale.

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Building High-Quality Guidelines With BRIDGE-Wiz E-GAPPS at NYAM

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  1. Building High-Quality GuidelinesWith BRIDGE-WizE-GAPPS at NYAM Richard N. Shiffman, MD, MCIS Yale School of Medicine

  2. Overview • Essential background • Rationale: Why software? • Ideal recommendation • Action-types • Level of obligation • Building a recommendation

  3. Rationale • Key Action Statements (“recommendations”) differentiate guidelines from other publications • What to DO! • Shortcomings lead to difficulties in implementation • Often vague, underspecified, ambiguous • Unclear linkage of recommendation to supporting evidence • Expected level of adherence not explicit • Many panel members are unfamiliar with recommendation building • BRIDGE-Wiz program offers a systematic and replicable approach

  4. Authors Should Be Explicit About WHEN {under what circumstances} WHO {in the Intended Audience} Ought to {with what level of obligation} DO WHAT {To WHOM} {which members of the target population} HOW WHY IF THEN Denominator Numerator

  5. WEAK VERBS • Passive voice masks the actor • “Mistakes were made…” • “…should be prescribed/performed” • Direct recommendations to the guideline’s intended audience, not the target population • “Patients should receive…”

  6. Statement of Fact vs Recommendation • Anticholinergic agents are appropriate and effective treatment alternatives for the management of LUTS secondary to BPH • Urologists may prescribe anticholinergic agents for management of LUTS secondary to BPH if the patient does not have an elevated post-void residual AND LUTS are predominantly irritative.

  7. The Dreaded “Consider” • Pelvic floor muscle exercise treatment should be considered for patients following radical prostate surgery. • For women at or beyond 36 weeks of gestation with a first episode of HSV occurring during the current pregnancy, antiviral therapy should be considered. • Psychological therapy should be routinely considered as a treatment option when assessing mental health problems, including anxiety disorder

  8. Measurement • If you don’t measure it, you can’t manage it. (Drucker) • If you don’t measure it, you can’t improve it.

  9. Establishing Evidence Foundations for and Rating Strength of Recommendations 5.1 For each recommendation, the following should be provided: • An explanation of the reasoning underlying the recommendation, including: A clear description of potential benefits and harms. A summary of relevant available evidence (and evidentiary gaps), description of the quality (including applicability), quantity (including completeness), and consistency of the aggregate available evidence. An explanation of the part played by values, opinion, theory, and clinical experience in deriving the recommendation. • A rating of the level of confidence in (certainty regarding) the evidence underpinning the recommendation. • A rating of the strength of the recommendation in light of the preceding bullets. • A description and explanation of any differences of opinion regarding the recommendation.

  10. Articulation of Recommendations 6.1 Recommendations should be articulated in a standardized form detailing precisely what the recommended action is, and under what circumstances it should be performed. 6.2 Strong recommendations should be worded so that compliance with the recommendation(s) can be evaluated.

  11. Action-Types Gather Data Interpret Act Test Conclude Prescribe Procedure Monitor Educate/counsel Consult/refer Inquire Examine Advocate Document Prepare Prevent Dispose

  12. How “Should” We Write Guideline Recommendations • Web-based survey of 1332 registrants to AHRQ Annual Meeting • Presented 12 statements: • Participants indicated the level of obligation they believed guideline authors intended using a slider from No obligation to Full obligation (0 to 100)

  13. Level of Obligation

  14. Recommendations … 3a. Magnetic resonance imaging (MRI) is a non-invasive imaging test that produces high-quality and detailed images of the brain without the use of radiation. 3b. MRI (or other imaging modality) should be considered and neurological consultation requested for patients with new onset seizures when localizing signs are present on neurologic examination and CT scan is negative or headaches have been problematic. …

  15. S: patients with new onset seizures AND • L: localizing signs are present on neurologic examination AND • C: CT scan is negative OR • H: headaches have been problematic S AND (L AND C) OR H (S AND L) AND (C OR H)

  16. Bridge the Gap Between Authors and ImplementersWith BRIDGE-Wiz(Building Recommendations In a Developer’s Guideline Editor)

  17. Thank you!

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