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ZIKA CASES (1/15 -9/7/16)

This resource provides information on Zika virus cases in the United States and US territories, including travel-associated and locally acquired cases. It also highlights the risks of Zika transmission through blood transfusion and organ transplantation.

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ZIKA CASES (1/15 -9/7/16)

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  1. ZIKA CASES (1/15 -9/7/16) USA- 2,964 total • Travel associated 2,920 • Locally acquired mosquito borne cases 43 • Lab acquired 1 • Sexually transmitted 24 US TERRITORIES-15,869 (most locally acquired-not travel mainly PR, USVI & Samoa) NYS 734 (NYC 553)

  2. 80% asymptomatic • Incubation period 3-14 days • Viremia: after symptom onset-days to 1 wk (some cases longer) • Zika RNA+ in semen 6 mo after • Can be negative in blood but + in placenta & semen (very limited data)-

  3. FDA guidance on tissue (3/2016) • FDA identifies zika as a transfusion-transmitted infection-(8/26/16 guidance) • In a 2013 outbreak 2.8% samples from asymptomatic blood donors + zika RNA • In 2016 1% of blood donors in PR +zika • Probable transfusion transmission in Brazil

  4. ZIKA RISKS TO RECIPIENT • Flavivirus-same type of arbovirus as WNV • Antigenic cross talk with Dengue & WNV • Proliferates in immune system cells • WNV donor transmission-NYC 2005 • GB connection to Zika • Organ Trx pts: neuroinvasive disease 40X pop WNV; Zika 100X

  5. DTAC GUIDANCE • Focus on recent travel hx • Signs & Symptoms (Rash, fever, H/A, conjunctivitis) in donor • Living donors-defer donation, if possible • https://optn.transplant.hrsa.gov/news/guidance-on-zika-virus/ • Diagnostic and donor screening is limited/under development

  6. RESOURCES • NYSDOH Zika Info Line 888-364-4723 (M-F0 9AM-5PM) • Webinar for transplant professionals hosted by the NYSDOH-NYS Transplant Council September 22 12 noon • Hear from NYS public health experts & DTAC

  7. OTHER RESOURCES • NYSDOH – http://www.health.ny.gov/diseases/zika_virus/ • CDC Zika page http://www.cdc.gov/zika/ • FDA Zikahttp://www.fda.gov/EmergencyPreparedness/Counterterrorism/MedicalCountermeasures/MCMIssues/ucm485199.htm

  8. ZIKA WEBINAR INFO • Host: NYSDOH and the NYS Transplant Council • Date/time: Thursday, September 22nd 2016, 12 - 1 p.m. EST • Speakers: Kirsten St. George, MAppSc, PhD, Chief Viral Diseases, Wadsworth Center, NYSDOH; Lewis Teperman MD, FACS, Vice Chair of Surgery and Director of Transplant, Northwell Heath and Marian Michaels, MD, MPH, Professor of Pediatrics and Surgery, University of Pittsburgh School of Medicine, Disease Transmission Advisory Committee (DTAC) Vice Chair, United Network for Organ Sharing (UNOS) • Click here to register: https://meetny.webex.com/meetny/onstage/g.php?MTID=e580da9c168d10edd8994b963a60f4e4b

  9. NYSDOH CONTACTS • Nancey Agard RN, MS nancey.agard@health.ny.gov Lisa McMurdo RN, MPH lisa.mcmurdo@health.ny.gov 518-402-1003

  10. NYS HEALTH COMMERCE • A health professional can request an HCS account • http://www.health.ny.gov/prevention/immunization/information_system/providers/hpn_account_instructions.htm

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