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2008 IR-4 Food Use Workshop Sacramento, CA

2008 IR-4 Food Use Workshop Sacramento, CA. Nichino America Inc. Jim Adams, Manager, Product Development Marie Maks-Regulatory Affairs Manager Phone: (302) 636-9001 Web site: www.nichino.net. Tolfenpyrad. NAI-2302 15EC NAI-2303 15SC. Chemical Details on Tolfenpyrad.

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2008 IR-4 Food Use Workshop Sacramento, CA

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  1. 2008 IR-4 Food Use WorkshopSacramento, CA Nichino America Inc. Jim Adams, Manager, Product Development Marie Maks-Regulatory Affairs Manager Phone: (302) 636-9001 Web site: www.nichino.net

  2. Tolfenpyrad NAI-2302 15EC NAI-2303 15SC

  3. Chemical Details on Tolfenpyrad • Chemical Name: 4-chloro-3-ethyl-1-methyl-N-[4-p-tolyloxy)benzyl] pyrazole -5-carboxamide • Empirical Formula: C21H22Cl N3O2 • Molecular Weight: 283.9 • Code Number: NAI-2302

  4. Insects Controlled • Hemiptera, Coleoptera, Diptera, Lepidoptera, Thysanoptera, and Acarina • Poisoning by ingestion; contact activity; anti-feeding activity against leps • Target Crops: • Vegetables, Cucurbits, Cole Crops • Fruits & Nuts • Selected row crops • Ornamentals

  5. Efficacy Trials • Use rate 0.137 to 0.274 lb. a.i/acre (153-307 grams ai / hectare) • 14 – 27 oz/a (15% EC and 15% SC formulations) • Alternative mode of action useful against numerous vegetable and fruit/nut pests

  6. U.S. Registration Timeline • Submit non-crop indoor greenhouse use mid 2008 as reduced risk candidate • Submit crop uses with residue chemistry data by 2010 as reduced risk candidate

  7. Flubendiamide-Based Insecticides NNI-0771 NNI-0772 NNI-0776

  8. 2009 Introductions • NNI-0772 (Tourismo™) • Tree Nuts, Pome, Stone, Vines, Cotton • NNI-0871 (Vetica™) • Vegetables, Cucurbits, Cole Crops

  9. US Registration Timeline • Submission to EPA 2008 • Commercial Launch 2009

  10. Pyrifluquinazon NNI-0101

  11. Pyrifluquinazon (NNI-0101) • Hemiptera / Homptera • Rates: 12.5-50 grams ai/hectare • Whitefly, Aphids • Rates: 50-125 grams ai/hectare • Mealybug, thrips, leafhopper • Higher Rates: • Scale • True bugs

  12. Biological mode of action on aphids • NNI-0101 shows two distincteffects on aphids; • 1. Rapid response of abnormal behavior (insect dispersion, feeding cessation) • 2. Slow lethal action Appearance of activity/Green peach aphid Percent of dispersal insects (stop feeding) & mortality Abnormal behavior Death by starvation (insects may appear normal) of NNI-0101 treated insects of NNI-0101 treated insects Hours after treatment Figure 1. Mortality and percent of insect dispersal from treated plants of green peach aphid, Myzus persicae, after treatment with NNI-0101 at a dose rate of 50ppm.

  13. Possible IR-4 Interests • Onion thrips (PCR submitted) • Aphid, Thrip, Whitefly, Mealybug and Scale control on ornamentals • Rapid cessation of whitefly and aphid feeding reduces transmission of viruses vectored by these pests on important fruit and vegetable crops

  14. US Registration Timeline • Submit for food crop uses early 2010

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