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Micro fluidics in PCB technology

Flow injection analysis realized using PCBs S. Gassmann, L. Pagel Faculty of computer since and electronics Institute of Electronic Appliances and Circuits, University of Rostock, Rostock, Germany. Micro fluidics in PCB technology. University of Rostock PCB-Fluidics. Fluidic PCB-Technology.

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Micro fluidics in PCB technology

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  1. Flow injection analysis realized using PCBsS. Gassmann, L. PagelFaculty of computer since and electronicsInstitute of Electronic Appliances and Circuits, University of Rostock, Rostock, Germany

  2. Micro fluidics in PCB technology

  3. University of RostockPCB-Fluidics

  4. Fluidic PCB-Technology normal PCB production • drilling • milling

  5. Fluidic PCB-Technology normal PCB production • etching

  6. Fluidic PCB-Technology • second PCB stacked • copper lines build channels • gluing

  7. Fluidic PCB-Technology tube connection channel view

  8. Fluidic PCB-Technology cross section of channel

  9. Cross section of channel wall epoxy copper (2) copper (1) channel

  10. µC controlled programmable micro pump • Electrical connector • Power 4 –7 V DC • I2C - Bus • programming • 500µl/min Flow • 150 mBar max Backpressure • over USB-I2C IF fully programmable

  11. Flow-Injection-Analysis • quantitative measurement of components • automated procedure • short response times / high sample throughput • usage in quality control / automated assays • developed by J. Růžička and E.H. Hansen in the year 1975

  12. Flow-Injection-Analysis Sample Reagent Injection valve Detector Pump Reaction coil

  13. Reaction • Detection of Fe3+ • Thiocyanate as reagent • forms red colored Iron-Thiocyanate • detection by absorption at 480 nm

  14. Why a FIA? • All basic fluidic handling necessary - transportation of fluids - dosing of fluids - mixing - detecting - adoption to detection needed - electronics needed

  15. FIA in PCB-Technologie Principle injection detector reagent pump photometrical 480 nm reaction coil sample pump • 2 separate controllable pumps • no injection valve • optical detection

  16. MIXING Flow pattern in 180° curves

  17. Simulation results of the used reaction channel Parameters: 2 pumps with constant flow of 0.2ml/min Fluidsimulation: FLOWORKS 789388 cells

  18. … and the reality

  19. Simulation results of the used reaction channel parameters: thermopneumatically actuated pumps with pulsing flow of 0.2ml/min, 789388 cells

  20. Simulation results of the reaction channel vector plot of the fluid velocity at the cross section of the channel after the second curve parameters: thermopneumatically actuated pumps with pulsing flow of 0.2ml/min, 789388 cells

  21. OPTICAL SENSOR in FIA

  22. Optical Cell with air bubble (vector of the force)

  23. Realization • stack of four PCBs • one movable layer • of polyimid • electronics on the back • of the fourth PCB 5 cm 5 cm

  24. FIA Realization

  25. FIA in PCB with integrated electronics

  26. Signals in the photo detector in dependence on the concentration of Fe(III)ions

  27. PCB FIA facts • Detection Fe3+ Ions • 0,16 mMol – 10 mMol • reproducibility peak height 5%, peak area 10% Monolithic system consisting fluidics and electronics in one stack of PCBs.

  28. Thank you for your attention!

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