Welcome to Bio181L!

1. Welcome to Bio181L! • Contemplating the nuts & bolts of Life • “It’s atoms all the way down”

2. About me...

3. About you • Name • Where you are from • Major and year (freshman, sophomore, etc.) • What you do in your free time • What you want to do when you graduate • What you tell your relatives (may be the same)

4. What 181L is • Thinking, Understanding, Investigating, Evaluating • Not arrive, assembly line, leave • Manual pp. ix & xi should help • Not sync’ed with most lecture sections, but internally coherent & mutually reinforcing

5. Expectations • Read the lab manual BEFORE lab • Be ON TIME to class • PARTICIPATE • Complete the assignments (online, etc) • Participate

6. About the manual • Reading it will prepare you for class & in-class quizzes • Reading prior to 5’ before class will allow you to understand & think about what you’re reading • Lays out Philosophy (vii), Learning Goals (ix), expectations (xi) • Contains Periodic Table (0-1) and Molecular Basics (0-3), rules of molecule pics (0-5) and a cell (0-7)

7. 181 Lab ACCOUNTS • http://blc.arizona.edu/courses/181lab (Safari home page) • Click ‘Create Accounts’ • Your section number is: ## • Bio181L_Go is the way to do your work. Browser bad

8. Where to find 181L_Go and a movie explaining how to download it to your computer

9. 80% of success is just showing up* • Absences must be excused by Asya Roberts in BSE109 prior to making up. Contact her as soon as possible. Really. • Late is absent. Leaving early is absent. • Labs cannot be offered week after they are delivered; Avoid missing a lab • Missing 2 labs => you’ll be dropped from the course--excused or otherwise (b/c you’ll have little shot at learning what you need) *--Woody Allen

10. My Webpage • Get there via homepage* => Instructors => Sxn# *http://blc.arizona.edu/courses/181Lab (Lab Man yellow page)

11. Web page operation

12. Policies & Grading • Syllabus (Linked on course homepage) • Honor code & Plagiarism (Manual, p. xiii) • Assignments • On-line assessments/tutorials (10%) • In-class quizzes (15%) • Lab assignments (LABAs--Lab Activity Based Assignments) (50%) • Lab Projects & reports (combine to 25%) • Every assignment is posted & reported on basis of 100% • For electronic assignments, log in again to see your recorded score • Also reported to you at the end

13. How? Why? the Tao of Molecules • How molecules feel & the world they live in

14. Primary goals • Creating understanding by observation and reasoning • Establish the chemical foundations for the course: • Water & its properties • non-watery things • Start thinking of molecules as real & tangible

15. What do you know about oil and water?

16. What do you know about oil and water? • Today is all about understanding what you “know”

17. When a journalist asked the great physicist Richard Feynman what single sentence would best encapsulate all science so far if it were to be the sole surviving scrap of all we knew, he replied,“The world is made of atoms.” From The Secret of Scent, Luca Turin p.28

18. Atoms: They’re how life works • DNA, RNA: C, H, N, O, P, [Mg++] • Carbs: C, H, O • Protein: C, H, N, O, (S), (P), [traces] • Membranes: C, H, N, O, P, (S) What cannot be done with assemblages of these atoms* cannot be doneby living organisms, nor their cells, nor their spit, etc. *OK, fine, there’s the occasional role for Ca++, etc.

19. Who am I? • At birth, # protons = # electrons • Atoms seek completion, which means outermost electron set = 8 (hydrogen, helium it’s just 2) Freeman Fig. 2.1a

20. Dependent on: # protons (+ve charge) Distance e- from nucleus Slide courtesy of Cara Gibson

21. Symbolizing • Atoms & Molecules

22. Coloring your world **memorize these – they will be on your quiz next week

23. + O H H + - Views of Water (There will be a test) H2O See lab manual, p. 0-3

24. RED also means ‘negative’ Blue also means ‘positive’ More on colors

25. Interacting with H2O To your StructViewers! Desktop => Bio181L_Go

26. Doing it • Computers, stations • Write your group name down; otherwise you can’t retrieve your work!

27. Group names: Just use the first three letters of everyone’s name • i.e., emikevbru • Write this down so you can look at your work latter if you want to • You will all just go until you get to the stuff about alcohols and salt and then we will talk again

28. How to draw molecules Carbon HydrogenOxygenNitrogen Figure is from Lab Manual p. 0-5

29. TA-lead discussions

30. “Salting out” • It’s a real term; used to refer to a situation where the addition of salt (portable charges) alters the solubility of other molecules in water • Why should this be?

31. Evaporation • First things first--what is it? What’s going on in terms of molecules • Experiment: Ethanol and water on your arm: which is cooler & why? • Prediction: based on molecular weight, which should evaporate more quickly--H2O (2 x 1 + 1 x 16) or CH3CH2OH (5 x 1; 2 x 12; 1 x 16) • If not, why not? • Salt--ever tasted your sweat? Or anybody else’s for that matter? • What benefit might there be to adding NaCl to water that you are intending to evaporate?

32. Clean up! • Oil waste in the hood • ethanol waste in the sink • anything too messy wadded up and discarded

33. Some advice http://www.damnlol.com/please-do-me-right-now-224.html

34. What’s an Assessor? =>Chatting<=

35. What’s vocabulary homework? • EITHER both versions of the crossword exercise • OR VocabuWary with a better than threshold score • For “Atoms & Molecules”, F12, that’s 60,000 • Errors count off. Slowness counts off.

36. Homework due 10 p.m. before lab Extensive! In Depth! Next week’s quiz will include Concepts from today Atom colors Deducing partial charges (from tutorial) Manual Ch. 2 • Assessor: 181 Intro ’12 • Vocab Atoms/Mols: xWord(x2) or‘Wary • Assessor: Molecular World Tutorial