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TA sections. Choose the ones you want. Go to them. Not required, but a good idea. Start Monday Sept 30. rh. My office hours. 2130 Pacific Hall. Tues 2:30-3:30. Wed 2:30-3:30. rh. Metabolic Biochemistry BIBC 102. hppt://courses.ucsd.edu/rhampton/bibc102. office hours 2130E Pac Hall.
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TA sections Choose the ones you want Go to them Not required, but a good idea Start Monday Sept 30 rh
My office hours 2130 Pacific Hall Tues 2:30-3:30 Wed 2:30-3:30 rh
Metabolic Biochemistry BIBC 102 hppt://courses.ucsd.edu/rhampton/bibc102 office hours 2130E Pac Hall Tues 2:30 - 3:30 Wed 2:30 - 3:30 exams 1 midterm, 1 final problem sets available on web TAs conduct sections: best to choose one
How to take this class 1) Bring the lecture slides TO CLASS you can: a) download and print
-ready soon -pages with holes -2 slides per page (by popular demand) How to take this class 1) Bring the lecture slides TO CLASS you can: b) buy a packet at Soft reserves
How to take this class 2) Know everything on the study list 3) Know all the terms on the terms list
How to take this class 2) Know everything on the study list 3) Know all the terms on the terms list 4) Take advantage of the problem sets
C6H12O6 Podcasting… with benefits podcasts on web ~24 hrs after class
iClicker 2 Why? • Allows instant feedback and • refocusing 2) Pleasantly anonymous 3) Facilitates my teaching 4) Provides easy source of points
iClicker 2 1) Get one. Must be “iClicker brand Sold in UCSD bookstore 2) Bring it to class, use it 3) Credit given for participation not correctness
In-class text messaging… Ask… or txt: 858 914 4945
make sure you can check your UCSD email (@ucsd.edu)
Nelson, Cox and Lehninger 6th Ed. fifth edition sixth edition
Nelson, Cox and Lehninger 5th Ed. This year, NC&L is suggested, But NOT required…
familiar biomolecules
small biomolecules are “non-iterated” but do have common functional groups
small biomolecules are “non-iterated” but do have common functional groups fig1-16
Why study and understand metabolism? 0) Underlies every life process at some level 1) Obesity: a world-wide problem in health 2) Adult onset diabetes: a metabolic disease 3) Exercise and metabolism 4) Important in ageing, cancer and many other maladies 5) Biofuel strategies for alternative energy rh
catabolism and anabolism
Just because it isn’t a lab course doesn’t mean we can have a guinea pig… Life: a balance of catabolism and anabolism mass exercise caloric input activity
The Stedman Institute at Duke U. School of Medicine Chris Newgard
an amino acid an L amino acid
Amino acids: The Molecular Tool Box fig3-5
Amino acids: The Molecular Tool Box (C) (S) (T) (V) (A) (G) (P) (L) (I) (M) (N) (Q) (D) (E) (W) (F) (Y) (K) (R) (H) fig3-5
Amino acids: The secret practice method
A polypeptide with 5 residues has distinct ends or termini: N and C
met-enkephalin: a neuropeptide Tyr-Gly-Gly-Phe-Met your own morphine
The a helix fig 4-4
The a helix fig4-6
The b sheet fig4-19
The b sheet fig4-6
common b structures fig4-19
examples of folded proteins with a and b 2o structures fig4-21