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Endotracheal Intubation in Patients With Cervical Spine Instability. Secure airway without causing/worsening neurologic injuryThese patients are often a
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1. AIRWAY MANAGEMENT IN PATIENTS WITH UNSTABLE CERVICAL SPINESSTRATEGIES AND TECHNIQUES Brad Hindman, M.D.
Department of Anesthesia
University of Iowa, College of Medicine
2. Endotracheal Intubation in Patients With Cervical Spine Instability Secure airway without causing/worsening neurologic injury
These patients are often a “difficult intubation”
Disease process
Methods to stabilize cervical spine
3. Motion & Force During Conventional Direct Laryngoscopy & IntubationNormal Spine
4. Normal SpineCervical Spine Motion during Direct Laryngoscopy/Intubation
5. Normal SpineLifting Force during Direct Laryngoscopy/Intubation a,b
6. SummaryNormal Cervical Spines Cervical motion may be reduced by limiting glottic exposure
Poor glottic view could pose risk with unstable cervical spines
“Too much” force across unstable segments
7. Motion & ForceConventional Direct Laryngoscopy & IntubationUnstable Spine
8. Unstable Cervical Spine Moves abnormally with motion/force of laryngoscopy
Where pathologic motion occurs depends on
Specific location & nature of instability
Force applied across unstable segment
9. Unstable SpineO-C1-C2 Complex Laxity of Transverse Ligament (Rheumatoid Arthritis, Down Syndrome)
Flexion: Odontoid moves posteriorly towards cord
Intubation (extension): Theoretically, not at risk
Abnormal odontoid and/or O-C1-C2 articulations
Flexion/Extension: C1 subluxes on C2, compressing cord
Intubation (extension): AT RISK
Combined bony & ligamentous abnormalities - ?
10. Unstable SpineSub-axial Segments (C3-C7)Spine Movement during Laryngoscopy/Intubation
11. SummaryUnstable Cervical Spine Difficult to predict net spine motion during laryngoscopy
When cervical spine instability present
Minimize force applied across unstable segments
Minimize cervical spine motion
Maintain neck in neutral position
12. Effects of External Cervical SpineStabilization MethodsNormal Spine
13. Normal SpineCollars and Manual In-Line Stabilization (MILS) Concept: Prevent spine movement during intubation
Majernick TG: Ann Emerg Med 1986; 15:417
16 normal subjects
Collars did not reduce spine motion
MILS did appear to reduce spine motion
14. Normal SpineEffect of MILS during Direct Laryngoscopy & Intubation
15. Effects of External Cervical SpineStabilization MethodsUnstable Spine
16. Unstable SpineEffect of Stabilization Aprahamian C: Ann Emerg Med 1984; 13:584
1 cadaver: complete C5-C6 ligamentous instability
Rigid Collar did not appear to affect spine movement
Donaldson WF: Spine 1993; 18:2020
5 cadavers: incomplete C5-C6 ligamentous instability
“Head stabilization” may have ? subluxation & angulation
Lennarson PJ: J Neurosurg (Spine 2) 2000; 92:201
16 cadavers: incomplete C4-C5 ligamentous instability
MILS did not prevent abnormal flexion
17. Unstable SpineComplete ligamentous laxity at C4-C5a
18. Unstable SpineAxial Traction Can result in severe distraction
Bivins HG: Ann Emerg Med 1988; 17:25
Donaldson WF 3rd: Spine 1993; 18:2020
Axial traction is to be avoided during intubation, unless...
19. Unstable SpineEffect of MILS with O-C1-C2 Instability
20. SummaryExternal Stabilization Maneuvers & Spine MovementDuring Laryngoscopy and Intubation Axial Traction
O-C2: Probably dangerous
C3-C7: Probably dangerous
Cervical Collars
O-C2: ?
C3-C7: No indication of benefit
MILS
O-C2: May be of benefit, maybe not
C3-C7: May be of benefit, maybe not
Nevertheless, it is the standard of care
21. Method of Manual In-Line Stabilization (MILS)During Conventional Direct Laryngoscopy Patient supine, head flat on table in neutral position
Assistant
Grasps both mastoid processes with fingertips
Cup occiput in hands without applying axial traction
Anterior portion of cervical spine collar removed
Allows maximal mouth opening
Expose anterior neck (cricoid pressure, retrograde wire, or surgical airway)
22. Method of MILS, continued Preoxygenation (& cricoid pressure if “full stomach”)
Sedatives/anesthetics & paralytics as indicated
Assistant applies force(s) equal & opposite to those of DL to keep the head/neck in neutral position
23. By limiting extension at O-C2MILS often worsens glottic view with conventional DLGlottic View with Standard Head & Neck Position vs. MILSa
24. MILS & Conventional Direct Laryngoscopy ~10% risk of not seeing glottis
Lifting harder may not be advisable
Airway aids (bougie, light wand, fiberoscope)
Alternatives to Conventional Direct Laryngoscopy
Bullard, WuScope, Intubating LMA
25. Clinical Scenarios & General Approachesto Endotracheal IntubationEmergent Intubation with Traumatic Cervical Spine Injury
26. Emergent Intubation and C-Spine Trauma/InstabilityThe Cervical Spine in the Setting of Trauma 2-4% of blunt trauma patients have C-spine fx/dislocations
Cluster around C1-C2 & C5-C6
70% have major associated injuries
50% have neurologic signs/symptoms
25-50% require intubation within 24 h
Before complete/definitive C-spine evaluation
In presence of known instability
Effect of DL/intubation difficult to predict
27. Emergent Intubation and C-Spine Trauma/InstabilityNeurologic Injury from Conventional DL & Intubation“Low” but Real Hastings RH: Anesthesiology 1993; 78:580
Unrecognized fx at C6-C7
Muckart DJJ: Anesthesiology 1997; 87:418
2 patients: Unrecognized fxs at C2 & C6
Redl G: Anesthesiology 1998; 89:1262
Unrecognized C2 instability
28. Emergent Intubation and C-Spine Trauma/InstabilityAdvanced Trauma Life Support (ATLS) Guidelines-1980’s Blind nasotracheal intubation for emergent intubation
(n=1) Aprahamian C: Ann Emerg Med 1984; 13:584
(n=7) Bivins HG: Ann Emerg Med 1988; 17:25
Problems
Often not easy
Often not fast
Often not successful
Sometimes contraindicated (basilar- mid-face fx)
29. Emergent Intubation and C-Spine Trauma/InstabilityIntubation Methods In Patients with Acute Cervical Spine Injury
30. Emergent Intubation and C-Spine Trauma/InstabilityRisk of Neurologic Injury Conventional Direct Laryngoscopy & MILS (±anesthesia, ±paralysis)
0/374: 95% confidence: 0-1%
Awake Nasotracheal Intubation
0/240: 95% confidence: 0-2%
31. Emergent Intubation and C-Spine Trauma/InstabilityAdvanced Trauma Life Support (ATLS) Guidelines-NOW
32. Emergent Intubation and C-Spine Trauma-InstabilityConventional DL & Intubation with MILS/Trauma Failed intubation reported 2-10%
MILS can limit glottic visualization
Blood & secretions
Altered anatomy (prevertebral swelling)
Difficult Airway algorithm (Caplan RA: Anesthesiology 1993; 78:597)
33. Clinical Scenarios & General Approachesto Endotracheal IntubationNON-Emergent Intubation with Cervical Spine Instability
34. NON-Emergent Intubation with Cervical Spine InstabilityRosenblatt WH: Anesth Analg 1998; 87:153
35. NON-Emergent Intubation with Cervical Spine InstabilityAirway Anesthesia Supraglottic (Superior Laryngeal Nerve)
Internal br.: Sensory: Pharynx to false cords
External br.: Motor to cricothyroid muscle
Blockade: Thyrohyoid membrane or pyriform fossa
Subglottic (Recurrent Laryngeal Nerve)
Sensory: True vocal cords to trachea
Motor: Intrinsic muscles of larynx
Blockade: Transcricoid injection of local anesthetic
Combined (Topical)
Inhalation f nebulized local anesthetic
36. NON-Emergent Intubation with Cervical Spine InstabilityAirway Anesthesia Nasal Mucosae (Trigeminal)
Anesthesia and vasoconstriction
4% cocaine or 3-4% lidocaine/0.25-1.00% phenylephrine
Oral/Gag (Glossopharyngeal)
Lingual br.: Posterior 1/3rd of tongue
Blockade: Palatoglossal arch (injection or topical)
37. Airway Anesthesia: Topical vs. BlocksReasoner DK: J Neurosurg Anesth 1995; 7:94
38. NON-Emergent Intubation…, FiberopticsDifficulties Encountered during Elective Fiberoptic Intubation in Patients with Cervical Spine Diseasea,b,c,d
39. NON-Emergent Intubation…, FiberopticsEndotracheal tube “catching” on Glottic Structuresa
40. NON-Emergent Intubation…, FiberopticsEndotracheal tube “catching” on Glottic Structures
41. NON-Emergent Intubation…, FiberopticEndotracheal tube “catching” on Glottic Structures Rotate tube counterclockwise during advancement
Pull tongue forward during advancement
Patient persistence
42. NON-Emergent Intubation with Cervical Spine InstabilityThe Bullard Laryngoscope
43. NON-Emergent Intubation with Cervical InstabilityThe Bullard Laryngoscope Potential Advantages
Can be faster than fiberoptics
Neck can be maintained in neutral position
Better glottic visualization with MILS
44. NON-Emergent Intubation with Cervical Spine InstabilityConventional Laryngoscopy vs. Bullarda
45. NON-Emergent Intubation with Cervical Spine InstabilityThe Bullard Laryngoscope Notes of Caution
Significant “learning curve”
Not evaluated in patients with unstable spines
Successful intubation not “a sure thing”
15% failure (MacQuarrie K: Can J Anesth 1999; 46:760)
46. NON-Emergent Intubation with Cervical Spine InstabilityThe WuScope
47. NON-Emergent Intubation with Cervical Spine Instability WuScope & MILS vs. Conventional DL & MILSa
48. NON-Emergent Intubation with Cervical Spine InstabilityThe WuScope Potential Advantages
Neck can be maintained in neutral position
Better glottic visualization with MILS
Notes of Caution
Learning Curve
Not evaluated in patients with unstable spines
Not a “sure thing”
49. NON-Emergent Intubation with Cervical Spine InstabilityThe Intubating LMA (ILMA)
50. NON-Emergent Intubation with Cervical Spine InstabilityThe ILMA Can be inserted with head & neck neutral
Designed to allow rapid blind orotracheal intubation
Fiberoptic guided intubation also possible
Case reports of use in patients with unstable spinesa,b
a. Schuschnig C: Anaesthesia 1999; 54:793
b. Wong JK: J Clin Anesth 1999; 11:346
51. NON-Emergent Intubation with Cervical Spine InstabilityThe ILMA Patients in Cervical Collarsa
Placement generally difficult
Ventilation poor 40%; blind intubation success 20%
Patients with Cervical Spine Disease (25% unstable)b
?2 attempts to place 25%
Blind intubation success 63%; esophageal intubation 8%
Patients with Cervical Spine Disease (15% unstable)c
?2 attempts to place 45%
C2-C5 displaced posteriorly; 1.5-3.0° of flexion
a. Wakeling HG: Br J Anaesth 2000; 84:254
b. Nakazawa K: Anesth Analg 1999; 89:1319
c. Kihara S: Anesth Analg 2000; 91:195
52. NON-Emergent Intubation with Cervical Spine InstabilityThe ILMA Cadavers with Stable Necksa
ILMA Insertion/adjustment: 200-400 cm H2O pressure on C2-C3
C3 displaced 1-3 mm
Cadavers with Unstable Necks (posterior C3)b
ILMA 1.7±1.3 mm post. displacement
Conventional DL 2.6±1.6 mm post. displacement
Combitube placement 3.2±1.6 mm post. displacement
Nasal Fiberoptic 0.1±0.7 mm post. displacement
a. Keller C: Anesth Analg 1999;89:1296
b. Brimacombe J: Anesth Analg 2000; 91:1274
53. NON-Emergent Intubation with Cervical Spine InstabilityThe ILMA Notes of Caution
Multiple attempts to correctly place often necessary
Relatively low success rate with blind intubation
High pressure on C2-C3, risk of spine displacement