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ANUS – What can it show us…..?. Chris Driver RACH. Definition… . >4mm @ any stage of gestation? >5mm @ any stage of gestation? >7mm @ 30 weeks? >10mm……?. Diagnoses…. normal – 90% VUR NONRMU VUJ obstruction posterior urethral valves MCD kidney duplication anomalies PUJ obstruction
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ANUS – What can it show us…..? Chris Driver RACH
Definition… • >4mm @ any stage of gestation? • >5mm @ any stage of gestation? • >7mm @ 30 weeks? • >10mm……?
Diagnoses….. normal – 90% VUR NONRMU VUJ obstruction posterior urethral valves MCD kidney duplication anomalies PUJ obstruction …….!
PNUS • Day 0 • underestimates c/w ANUS • early management of severe abnormality • 6 week • definitive scan • will be “worse” than day 0
VUR • “dilating” reflux only • more likely to get better c/w PNDx • Plan: • Antibiotic prophylaxis • MCUG • DMSA
Hyroureteronephrosis • VUR • VUJ obstruction • Non obstructing non refluxing megaureter • Plan • MCUG • MAG3 (age >3 months) • Antibiotic prophylaxis (until VUR excluded)
NONRMU vs VUJ ….? • exclusion essentially • cytsocopy and retrograde – “rats tail” • clues: • increasing HUN • reduced function
NONRMU vs VUJ ….? • Plan: • observe • JJ stent insertion • diagnostic +/- therapeutic • TUU • reimplant
Posterior Urethral Valves • bladder outflow obstruction • unilateral (good) or bilateral (bad) HUN • oligohydramnios (bad)
Posterior Urethral Valves • Plan: • MCUG +/- catheter • bloods • optimised fluid management • antibiotic prophylaxis • valve resection +/- vesicostomy
Multicystic dysplastic kidney (MCDK) • failure of fusion of ureteric bud and developing kidney • 0% Function on DMSA • risks minimal
Multicystic dysplastic kidney (MCDK) • Plan • PNUS • DMSA • Default is non-operative
PUJ “obstruction” dilatation ¹ obstruction isolated hydronephrosis aetiology intrinsic extrinsic
PUJ “obstruction” • Plan: • PNUS • MAG3 ->3 months • no need for prophylaxis
Options? • observe • serial USS • occasional renogram • DMSA more accurate for function • operate
kidney ureter renal pelvis Dilated pelvis Tortuous ureter
ANUS and PUJO – Is size important? • GOSH data on PNUS • >35mm comes to surgery eventually • when can we leave alone? • unclear • <10 mm – surgery rare • <19mm – 5% come to surgery (unpublished) • but ……around 3% deteriorate over time • usually 1st 2 years
ANUS advantages permits early detection of renal pathology ?intervening early improves overall outcome? disadvantages no evidence base for criteria for intervention no consensus for early discharge increased parental anxiety