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“Mad Honey” poisoning – Increasing Knowledge and Reducing the Risk. Hope Thompson PUBH 6165-4 November 4, 2009. What is “mad Honey” poisoning?.
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“Mad Honey” poisoning – Increasing Knowledge and Reducing the Risk Hope Thompson PUBH 6165-4 November 4, 2009
What is “mad Honey” poisoning? Honey intoxication is caused by the eating of honey produced from the nectar of rhododendrons. The grayanotoxins cause the intoxication. This can lead to dose-dependent hypotension, bradycardia, and respiratory-rate depression. Bad Bug Book: Foodborne Pathogenic Microorganisms and Natural Toxins Handbook. (2009, May 4). Retrieved September 24, 2009, from U.S. Food and Drug Administration: http://www.fda.gov/Food/FoodSafety/FoodborneIllness/FoodborneIllnessFoodbornePathogensNaturalToxis/BadBugBook/ucm071128.htm Cagli, K. E., Tufekcioglu O., Sen N., Aras D., Topaloglu S., Basar N., & Pehlivan S. (2009). Atrioventricular Block Induced by Mad-Honey Intoxication. Texas Heart Institute Journal, 342-244.
What Are The Symptoms? Dizziness, nausea, vomiting, excess sweating, hyper salvation, and weakness are usually seen within 1-2 hours of intoxication and typically last no more than 24 hours. Gunduz A., Turedi S., Russell R. M., & Ayaz F.A. (2008). Clinical review of grayanotoxin/mad honey poisoning past and present. Clinical Toxicology, 437-442.
Pre - Prevention What can be done to prevent mad honey poisoning in the first place?
During - Prevention Once a person falls victim to mad honey poisoning, what should he/she do?
Treatment Regular supportive care with electrocardiographic monitoring, intravenous atropine, and saline infusion serve as successful forms of treatment Gunduz A., Turedi S., Russell R. M., & Ayaz F.A. (2008). Clinical review of grayanotoxin/mad honey poisoning past and present. Clinical Toxicology, 437-442.
Post - Prevention How can individuals protect themselves in the future?
Stop the “Mad”-Ness Honey! Since conditions are rarely persistent, lasting no more than a day and hardly lead to death, is it possible to completely eradicate mad honey poisoning?
Stakeholders General public, restaurant managers, farmers (particularly small owned farms), CDC, poison control centers, and public health clinics/hospitals
Thank You! Many thanks for your time and patience. I hope that you found the presentation informative.
References Bad Bug Book: Foodborne Pathogenic Microorganisms and Natural Toxins Handbook. (2009, May 4). Retrieved September 24, 2009, from U.S. Food and Drug Administration: http://www.fda.gov/Food/FoodSafety/FoodborneIllness/FoodborneIllnessFoodbornePathogensNaturalToxis/BadBugBook/ucm071128.htm Cagli, K. E., Tufekcioglu O., Sen N., Aras D., Topaloglu S., Basar N., & Pehlivan S. (2009). Atrioventricular Block Induced by Mad-Honey Intoxication. Texas Heart Institute Journal, 342-244. Dilber E., Kalyoncu M., Yaris N., & Okten A. (2002). A Case of Mad Honey Poisoning Presenting with Convulsion: Intoxication Instead of Alternative Therapy. Turkish Journal of Medical Sciences, 361-362. Gunduz A., Turedi S., Russell R. M., & Ayaz F. A. (2008). Clinical review of grayanotoxin/mad honey poisoning past and present. Clinical Toxicology, 437-442. Laureate Education, Inc. (2008). Environmental Health [DVD].
Further Reading Lampe K. F. Rhododendrons, mountain laurel, and mad honey. JAMA 1988; 259:2009. Yavuz H, Ozel A, Akkus I, Erkul I. Honey poisoning in Turkey. Lancet 1991; 337:789–790. Koca I, Koca AF. Poisoning by mad honey : A brief review. Food Chem Toxicol 2007; 45:1315–318. White JW, Doner LW. Honey composition and properties. Beesource Web site. Available at: http://www.beesource.com/pov/usda/beekpUSA82.htm Yilmaz O. Eser M. Sahiner A., Altintop L., Yesildag O. Hypotension, bradycardia, and syncope caused by honey poisioning. Resuscitation 2006; 68(3):405-8.