PAN Foundation Offering Help and Hope for a Healthy Tomorrow

1. April, 2014 PAN Foundation Offering Help and Hope for a Healthy Tomorrow

2. Agenda • PAN Foundation Overview • Program Assistance • 2012 Patient & Provider Survey • Contact Information

3. Mission The Patient Access Network Foundation (PAN) offers help and hope to people with chronic or life-threatening illnesses for whom cost limits access to breakthrough medical treatments Background Established in 2004, PAN is an independent, national 501 (c) 3 organization Founded to help reduce the financial burden of underinsured critically and chronically ill patients and provide hope for leading productive and healthy lives again Governed by an 11-member Board of Directors with expertise in medicine, healthcare administration, non-profit management, finance and public policy Who We Are

4. What We Do • PAN provides financial assistance to individuals who have insurance but lack the means to pay for out-of-pocket costs associated with life-saving specialty medications • Who Qualifies • Individuals with Medicare, Medicaid or private health insurance who meet disease-specific eligibility criteria • Amount of Assistance • Depending on the illness, between $500 - $15,000 in copayment assistance for a 12-month period • Disease Funds • Nearly 60 disease-specific programs covering a wide range of patient needs

5. PAN Financial Assistance Programs Chronic Disease Rare Disease Oncology • Age Related Macular Degeneration • Ankylosing Spondylitis • Asthma • Chronic Iron Overload • Cytomegalovirus • Diabetic Foot Ulcers • Diabetic Macular Edema • Growth Hormone Deficiency • Hepatitis B • Hepatitis C • HIV/AIDS • Idiopathic Thrombocytopenic Purpura • Inflammatory Bowel Disease • Kidney Transplant Immunosuppressants • Multiple Sclerosis • Plaque Psoriasis • Postmenopausal Osteoporosis • Psoriatic Arthritis • Retinal Vein Occlusion • Respiratory Syncytial Virus • Rheumatoid Arthritis • Secondary Hyperparathyroidism • Solid Organ Transplant Immunosuppressants • Venous Leg Ulcers • Acromegaly • Cushing’s Disease • Gaucher Disease • Homozygous Familial Hypercholesterolemia • Methicillin-resistant Staphylococcus Aureus (MRSA) • Short Bowel Syndrome • Tuberous Sclerosis Complex • Uveitis • Wilson Disease • Advanced Basal Cell Carcinoma • Anaplastic Large Cell Lymphoma • Bone Metastases • Chemotherapy Induced Neutropenia • Chronic Lymphocytic Leukemia • Colorectal Cancer • Cutaneous T-cell Lymphoma • Gastrointestinal Stromal Tumors • Immunotherapy for Genitourinary Cancers • Hodgkin’s Lymphoma • Lung Cancer (Non-Small Cell) • Mantel Cell Lymphoma • Metastatic Breast Cancer • Metastatic Castrate Resistant Prostate Cancer • Metastatic Melanoma • Multiple Myeloma • Myelodysplastic Syndrome • Myeloproliferative Neoplasms • Non-Hodgkin’s Lymphoma • Progressive Neuroendocrine Tumors of Pancreatic Origin • Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia • Renal Cell Carcinoma • Well-Differentiated Thyroid Cancer Travel Assistance • Metastatic Castrate Resistant Prostate Cancer Premium Assistance • Homozygous Familial Hypercholesterolemia • Short Bowel Syndrome 5

6. By The Numbers • Since 2004 • PAN has helped more than 200,000 patients • Provided nearly $400,000,000 million in patient assistance • In 2013 • PAN received more than 330,000 calls • Approved nearly 91,000 applications • Processed applications in less than 1 minute • 98% approval rate • Partnered with more than 21,000 providers and 81 specialty pharmacies at 158 locations to help their patients obtain assistance from PAN

7. Program Assistance Relationship Flow: • Patient eligibility criteria: • Myelofibrosis (MF) • Polycythemia Vera (PV) • Essential Thrombocythemia (ET) • Patient has insurance coverage and is prescribed a high cost specialty therapy • Patient's income must be at or below 500% of the Federal Poverty Level • Patient must reside and receive treatment(s) in the US and its territories • $7,500 per year with the ability to receive additional funding, if available Patient Application Approval Letter Application PANFoundation Approval Letter SP/Provider 7

8. Application & Claims: A Rapid Response • Ability to “virtually “sign the application across all points of entry Staff approve patients according to PAN eligibility criteria Patients receive treatment PAN pays claims to pharmacies, physicians or patients Patients or Advocates seek assistance By Phone Website/Portals 8 PAN offers a variety of ways for patients, providers, and advocates to submit applications for financial assistance for high-cost specialty medications

9. Convenience Patients are issued an electronic benefit card to ensure seamless electronic submissions Name: John Jones ID #: PF100200 Group #: R2005 Rx Bin # 539355 • Offers access to our national network of pharmacies • Can be used by pharmacies or physicians to submit electronic or manual claims • Helps patients avoid making out-of-pocket payments for their medications 9

10. 2012 Impact & Satisfaction Survey • Objectives • Assess patient and provider satisfaction with PAN services • Understand effect of copay assistance on adoption of therapy and continuity of care • Key Findings • High out-of-pocket expenses associated with medications are #1 reason why patients fail to begin or continue treatment • Assistance from PAN helps patients comply with their medical regimen • Assistance from PAN allows patients to pay other bills, relieves stress, and positively impacts their overall health 538 Patient surveys completed; 430 Provider surveys completed

11. Copay Expense: #1 Barrier to Treatment Q. 1 Which factors, if any, affected your ability to begin the treatment recommended by your doctor? Q2. Which factors, if any, have affected your ability to continue (comply) with your treatment recommended by your doctor? (Check all that apply.) 2011 N=~500, 2012 N= 512

12. PAN’s AssistanceValuable Q3. Using a scale from 1 - 5 where 1 is Not at All Valuable and 5 is Extremely Valuable, please rate how PAN’s assistance has affected your ability to stay on track with your treatment? N=528

13. Patient ComplianceIncreased Percentage of patients able to take their medications as prescribed increased from 39% to 97% Before PAN's Assistance After PAN's Assistance Q.4 Prior to receiving assistance from PAN, were you able to take your medication as prescribed by your doctor? N=504 Q.5 Now that you are receiving co-payment assistance from PAN, are you able to take your medications as prescribed by your doctor? N=520

14. Proud To Say… 98% of patients are satisfied with PAN’s services 97% of providers select PAN as their first choice for financial assistance even when same assistance exists elsewhere

15. Summary Efficient and High Touch Service High Patient and Provider Satisfaction Strong Network of Physicians and Pharmacies Data-Based Decision Making 15

16. Contact Information www.PANfoundation.org 1-866-316-7263