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2009 NMVB Conference

2009 NMVB Conference. NYU Dept of Cardiothoracic Surgery NYU Dept of Pathology Friday December 4 th , 2009. Personnel @ NYU. Dept of Cardiothoracic Surgery: Harvey Pass, MD (surgeon, NYU steering committee member & PI) Audrey Sorensen, RN (research nurse coordinator)

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2009 NMVB Conference

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  1. 2009 NMVB Conference NYU Dept of Cardiothoracic Surgery NYU Dept of Pathology Friday December 4th, 2009

  2. Personnel @ NYU • Dept of Cardiothoracic Surgery: • Harvey Pass, MD (surgeon, NYU steering committee member & PI) • Audrey Sorensen, RN (research nurse coordinator) • Samantha Lincoln (data manager) • Ryan Harrington (lab technician, thoracic lab) • Angela Pittman (research project coordinator) • Dept of Pathology: • Jonathan Melamed, MD (pathologist, NYU steering committee member) • Jacinta Small (lab technician, pathology lab) • Tian He (research coordinator; previously Timothy Jolis) • Xiangtian Kong (pathologist, pathology review)

  3. 2008-2009 • Logistic improvements: • Streamlined specimen/case-notification process • Refined tissue procurement process with • response team and procurement kits • Synchronized local data • with MVB database • Progression on 5-year plans: • Frozen TMA • NYU MVB Paraffin TMA 1

  4. Mesothelioma Accrual Prospective cases: 63 Retrospective cases: 157 Total # of cases: 220

  5. Meso accrual data (cont’d) • Emphasis on accruing extrapleural pneumonectomy cases Tissue Collected (research blocks)

  6. Progression on 5 yr plans-Frozen TMA • Frozen TMA Frozen Array mold kit

  7. Frozen TMA

  8. Frozen TMA: Equipment & Accessories

  9. Plans for Paraffin TMA • NYU MVB Paraffin TMA 1 • Design Phase: • N= cases/ Block X 4 B • 4 TMA Blocks (same cases on each • block) • Control tissues, cell lines, frozen- • to-formalin tissue (adv: standardized • processing) • Construction Phase: MTA II • Microtomy: Limited number of sections; • histocollimator • Storage: In desiccators under nitrogen • atmosphere • High resolution scan of slide for website Sample paraffin TMA

  10. Paraffin TMA: Equipment & Accessories Tissue Micro-Arrayer Desiccators

  11. Proposed map for Paraffin TMA

  12. Special Thanks to… Today’s conference attendees And the entire NMVB team

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