1 / 10

The SICTO Study CYPHER TM S i rolimus-eluting stent in C hronic T otal O cclusion

The SICTO Study CYPHER TM S i rolimus-eluting stent in C hronic T otal O cclusion. Chaim Lotan MD, Yaron Almagor MD, Karel Kuiper MD, M.J. Suttorp MD, William Wijns MD. SICTO. STUDY DESIGN

toshi
Download Presentation

The SICTO Study CYPHER TM S i rolimus-eluting stent in C hronic T otal O cclusion

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. The SICTO StudyCYPHERTMSirolimus-eluting stentinChronicTotalOcclusion Chaim Lotan MD, Yaron Almagor MD, Karel Kuiper MD, M.J. Suttorp MD, William Wijns MD

  2. SICTO STUDY DESIGN A multicenter, prospective, non-randomized study to assess the feasibility and restenosis/reocclusion rates of coronary stenting with the CypherTM Sirolimus-eluting stent in patients with chronic total occlusion • 25 patients were treated with the CypherTM Sirolimus-eluting stent after successful balloon angioplasty and IVUS examination. • Clinical follow-up at 30 days, 6, 12, 18 and 24 months • - repeat angiography and IVUS at 6 months follow-up.

  3. SICTO- Baseline Demographics & Risk Factors

  4. SICTO - Baseline Angiographic & IVUS Data * IVUS estimate (N = 18),**QCA (N=25)

  5. SICTO - IVUS data6-month follow-up

  6. SICTO - Angiographic Data6-Month Follow-Up

  7. SICTO - Events to 6 months * 1 patient proximal +distal stenosis outside stent 1 patient distal dissection at index procedure,treated at follow-up

  8. Case from SICTO Study • Main complaint: severe shortness of breath and chest pain on mild exertion, increasing over last 6 months • Risk factors: Hyperlipidemia (10 y), DM (25y), HTN • 66 year-old female • Coronary angiography revealed diffusely diseased extremely small coronary arteries with a proximal occlusion in the LAD (arrow)

  9. Case fromSICTO Study Postprocedure 6 mos. follow-up Baseline • Patient underwent successful recanalization of the LAD with implantation of 2 long Cypher stents(2.5/23). • Patient’s condition improved significantly after procedure and returned to functional Class I. • Despite very long lesion (2 stents) in a very diffuse small artery, 6 months follow-up shows stents are widely patent. Chaim Lotan MD Hadassah-Hebrew University Medical Center, Jerusalem Israel

  10. In this feasibility study the CYPHERTM Sirolimus-eluting stent was very effective in the treatment of CTO, with verylow rates of TLR (0%), MACE (0%) and TVR (8%)compared to historical data with bare stents (30-50%). The CYPHERTM Sirolimus-eluting stent significantly inhibits intimal hyperplasia in CTO. These preliminary data will come in addition of larger database with CTO subpopulation (e.g. e-Cypher) SICTO– Conclusion

More Related