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Section 10.2. Meiosis. Genes, Chromosomes, and Numbers *organisms have tens of thousands of genes that determine individual traits. *genes are located on chromosomes; one chromosome can have as many as 1000 genes. A. Diploid and Haploid Cells
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Section 10.2 Meiosis
Genes, Chromosomes, and Numbers *organisms have tens of thousands of genes that determine individual traits. *genes are located on chromosomes; one chromosome can have as many as 1000 genes. A. Diploid and Haploid Cells 1. Diploid cells - a cell that contains 2 of each kind of chromosome (2n). a) in body cells of plants and animals, the chromosomes are usually found in pairs.
ex) humans = 46 chromosomes (23 pairs) b) one chromosome in each pair comes from each parent ex) one chromosome comes from male (dad), one comes from female (mom). *this supports Mendel’s conclusion that organisms have two (2) factors or alleles for each trait.
2. Haploid Cells - a cell with one of each kind of chromosome; contains the haploid or “half” the number “n.” a) gametes (sex cells) are haploid cells b) egg (n) + sperm (n) = zygote (2n) *this supports Mendel’s conclusion that each parent gives one factor, or allele, for each trait to the offspring.
B. Homologous Chromosomes 1. Homologous chromosomes - paired chromosomes with genes for the same trait that are arranged in the same order.
2. Gene order - on homologous chromosomes; genes are arranged in the same order, but the alleles on one gene of a chromosome may not beidentical to the alleles on the same gene of the other chromosome. II. The Importance of Meiosis and Its Phases A. Comparing Mitosis with Meiosis: 1. Mitosis - new cells have exactly the same number of kinds of chromosomes as the original cell (2n --> 2n). 2. Meiosis - a cell division which produces gametes, or sex cells, which contain only half the number of chromosomes as a body cell (2n --> n).
*meiosis occurs in the sex cells to make egg and sperm. Mitosis Meiosis 46 (2n) 46 (2n) 46 (2n) 46 (2n) 23 (n) 23 (n) B. Why is Meiosis so Important? *if mitosis was the only method for cells to divide, we would see a constant increase in the number of chromosomes with each reproduction.
ex) mom x dad mom x dad 46 46 46 46 child child 92 92 184 *each offspring formed by fertilization would have 2 times the number of chromosomes as each of the parents.
2. Meiosis keeps the number of chromosomes constant from generation to generation. mom x dad mom x dad 46 46 46 46 eggs(23) sperm(23) eggs(23) sperm(23) child child 23 + 23 = 46 23 + 23 = 46 child 46
C. Meiosis and the production of Sex Cells 1. Two (2) Phases of Meiosis: a) Meiosis I - begins with one diploid (2n) cell b) Meiosis II - ends with four haploid (n) cells 2. End Result: at the end of Meiosis II there are four (4) haploid cells; these cells are called sex cells or gametes. a) sperm - male gamete (n) b) egg - female gamete (n)
3. Zygote - the result of fertilization; the joining of an egg and a sperm. n + n = 2n 4. Sexual reproduction - the pattern of reproduction that involves the production and subsequent fusion of haploid sex cells. III. The Phases of Meiosis *interphase - the cell replicates its chromosomes; each cell consists of two identical sister chromatids held together by a centromere.
A. Meiosis I 1. Prophase I a) chromosomes coil up and spindles form b) duplicated homologous chromosomes pair up and form a tetrad. *tetrad - consists of two homologous chromosomes; each is made up of two sister chromatids.
c) crossing over - may occur during prophase I, this happens when non sister chromatids exchange genetic material when partnered up. *in prophase I of human meiosis there are an average of 2-3 crossovers per pair.
2. Metaphase I a) centromeres are attached to spindle fibers b) spindle fibers pull tetrads into the middle of the cell Tetrads are divided by the equatorial plate of the cell, remember that in mitosis sister chromatids are lined up and divided by the equatorial plate. Metaphase I Metaphase Meiosis (2n) Mitosis (2n)
3. Anaphase I a) Anaphase I begins as the homologous chromosomes (tetrads) are separated. Each chromosome, with its sister connected, gets pulled toward opposite ends of the cell. Anaphase I Anaphase meiosis (2n) mitosis (2n) b) Anaphase I ensures that each new cell will receive only one chromosome from each tetrad or homologous pair.
4. Telophase I *events occur in the reverse order of prophase I a) Spindle fibers are broken down as chromosomes reach their respective sides of the cell. b) Chromosomes begin to uncoil. c) Cytoplasm divides. *at the end of telophase, each new cell has only half the genetic info as the original cell because it has only one chromosomes from each pair; another division is still necessary to separate the sisters from each other,
Telophase: Telophase I Telophase meiosis (n) mitosis (2n)
B. Meiosis II *interphase period - very short; no replication takes place. 1. Prophase II a) spindle fibers begin to form in each of the two new cells. b) spindles attach to the chromosomes at the centromere.
2. Metaphase II a) chromosomes composed of both sister chromatids line up in the middle of the cell at the equatorial plate. They can no longer pair with their partners because their partners are in separate cells after meiosis I. b) the plate now divides sister chromatids, splitting them in half. *similar to metaphase of mitosis
3. Anaphase II a) centromere of each chromosome splits; now sister chromatids are separated and free to move. b) sister chromatids are pulled to opposite sides of the cell.
4. Telophase II a) spindle fibers break down. b) nuclei reform. c) cytoplasm divides, resulting in 4 haploid (n) daughter cells.
Meiosis II *steps of meiosis II are identical to mitosis, just happens with only half the information.
