Biopathology Center The Research Institute at Nationwide Children’s Hospital

1. Dave Billiter, MBA, PMP Director-Research Informatics Core Biopathology CenterThe Research Institute at Nationwide Children’s Hospital

2. Agenda

3. Biopathology Center

4. Biopathology Center • Biobanking • Biospecimen processing (procurement, testing, distribution, QA) • Informatics (data collection and distribution, biospecimen inventory, virtual microscopy, interactions with SDC and CG disease committees ) • Regulatory issues (CAP/CLIA certifications, MTA, informed consents, HIPAA) • Interactions with the Cooperative Group structure (SDC, Disease committees, Group Chair) • Disaster recovery initiatives (biospecimens, data) • Personnel (PhDs, MDs, MBAs, histotechnologist, medical technologists, biomedical engineers, computer scientists, electrical engineers, college students, sponsor project officers)

5. Biopathology Center • Central receiving • Specimens received (from >500 national and international institutions): fresh, frozen, FFPE, formalin fixed, blood, blood products, bone marrow, urine • COG: 88 protocols (open and closed) • GOG: 50 protocols (open and closed) • Receive Federal Express shipments Monday through Saturday • 70 to 100 packages a day (>1,000 biospecimens

6. Biopathology Center COG institutions submitting specimens to the COG Bank 2003 and June 30, 2009

7. Biopathology Center

8. End Goal

12. Workflows/Data Flows

13. Data Dictionaries

18. Current Solutions

23. Recommendations • Utilities/Tools focused on Non-Informatics/IT • -Ex. CDE Mapper (UI) • -Ex. Templates (.xls) • Refactor CDE Browser (User-Friendly) • -Ex. Ajax/JSON functionality • EDUCATION and OUTREACH!

24. THANK YOU!