Genomic Health U.S. New Hire Orientation

1. Genomic HealthU.S. New Hire Orientation Eileen T. Oncotype DX Patient

2. Your Agenda Today GHI’s 3-circles and Values Benefits Philosophy and Eligibility Health and Wellbeing Financial Accumulation & Income Protection Other Benefits Enrolment & Tools GHI Intranet, Compensation, Policies and Forms

3. The Genomic Health Model is Breaking Barriers to Personalized Medicine Improve the Quality of Treatment Decisions for Patients with Cancer Be the Best in the World at Development and Delivery of Personalized Genomic Information Maximize Value-Based Profit per Patient Served 3

4. Benefit Philosophy Genomic Health's benefits program is designed to: Protect you and your family against catastrophic financial loss Emphasize prevention and health maintenance Promote quality of life Allow the opportunity and encourage the accumulation of retirement savings Support excellence in our workforce Provide flexibility and choice to meet various employee needs

5. Benefits Eligibility You are eligible to enroll in benefits if you are a full-time employee working at least 30 hours per week You have 31 days from your hire date to make your benefit elections No default coverage Must wait until next open enrollment if benefits later desired Your benefits are effective as of your hire date After your initial enrollment you can only make changes if you have a “qualifying event” or during the next open enrollment in April Each year Open Enrollment is held in April with changes effective May 1st

6. Eligible Dependents You may also enroll your eligible dependents in the benefits program, including: your legal spouse your qualified domestic partner your unmarried children to age 19, or until age 25 if they are a full-time student at an accredited school and an IRS dependent Your children include: natural and adopted children stepchildren who are IRS dependents and who live with you in a parent-child relationship child(ren) of your qualified domestic partner any other children who are IRS dependents for whom you are the legal guardian or for whom you are required to provide coverage as the result of a qualified medical child support order

7. Qualifying Event The benefit choices you make when you enroll will remain in place for the entire plan year unless you experience a “qualifying event” or “change in family status” such as: The addition of a dependent through birth, adoption or marriage The loss of a dependent through divorce or death, or if your child reaches the maximum age limit for coverage The gain or loss of your dependent(s) coverage under another health plan If a qualifying event occurs in your life, you must adjust your benefits election within 31 days of the change by making a change in BeneTrac

8. Health and Wellbeing

9. Medical, Dental, Vision and FSA Plans Medical Kaiser HMO (available only in California) Anthem Blue Cross HMO (available only in California) Anthem Blue Cross PPO Anthem Blue Cross Lumenos HDHP w/HSA Anthem Blue Card PPO (only outside California) Anthem Blue Card Lumenos HDHP w/HSA (only outside California) Claremont EAP Dental Vision Flexible Spending Accounts (FSA)

10. Choosing the Right Medical Plan HMO (available only in California) Most benefits paid at 100% after $10 co-pay for office visits Care directed by your primary care physician Low out-of-pocket cost with little or no paperwork PPO or Blue Card PPO (only outside California) Co-pay of $10 for office visits Benefits paid at 90% or 70% depending on provider network status Self-directed care = freedom of choice Higher out-of-pocket cost and may require some paperwork

11. Choosing the Right Medical Plan Lumenos HDHP with HSA High deductible plan partially funded by GHI and lower payroll contribution More control over the use of your benefit dollars Long term benefit since left over funds in a HSA carry over and can grow year-to-year

12. How the HSA Plan Works Blue Cross Lumenos HSA – PPO High deductible: employee only $2,500 / family $5,000 Must also meet IRS eligibility requirements Meet the deductible, then benefits paid at 100% or 70% depending on provider network status Preventive care covered at 100% in-network with no deductible BUT all other services including Rx subject to deductible GHI funds half of the deductible over 12 months You can make additional pre-tax contributions to your account Annual federal limits = employee only $3,050 / family $6,150 Catch up contribution of up to $1,000 available for over age 50 Calendar year deductible so review your contribution amounts at the beginning of each year

13. IRS Eligibility and Rules for the HSA? You can only be covered by a HSA-compatible, high deductible plan if you have no additional coverage You cannot be enrolled in Medicare or, if 65, must waive Medicare You cannot be claimed as a dependent on another person’s tax return Employees in HSA can not participate in Health Care FSA Employees whose spouse is enrolled in a Health Care FSA can not participate in an HSA Dependent care FSA is separate from the healthcare FSA and does not conflict with the HSA

14. Claremont Employee Assistance Program Free services available to you and everyone living in your household Up to five confidential in-person counseling sessions per incident Stress and emotional issues Marital/relationship problems Parenting issues and eldercare assistance Dependent care consultation and referral Substance abuse, support groups, 12-step meetings Legal or financial consultations Member Access (800) 834-3773 www.claremonteap.com

15. Dental Plan Plan year maximum benefit $1,500 per person paid by plan Paid on payment schedule in table Plan year not calendar year May 1 to April 30 of the following year Covered benefits All dental care and / or orthodontia except cosmetic dentistry such as whitening and veneers You may see any dentist you choose and receive the dental care you need to stay healthy Higher benefits when you see in network dentists www.directdentalplans.com

16. How to Use Your Direct Dental Plan To use your Direct Dental Plan, present your ID card to your dental office Direct Dental will fax a Complete Benefit Summary to your dentist upon request Your dentist may mail or fax claim forms and receive payment directly from Direct Dental To help stretch your benefit dollars, the nation-wide network of PPO dentists offer an average discount of 20% to 30% on dental fees Visit www.directdentalplans.com and select the DHA link to find network dentists in your area!

17. Vision Plan Offered by VSP Eye exams may detect other health problems Eye Exam: once every 12 months Lenses: once every 12 months Frames: once every 24 months $10 exam & $25 materials co pay Use the VSP Network for richer benefits and preferred pricing $120 Frame Allowance Plus Discount On Balance $120 Contact Lens Allowance Polycarbonate Lenses For Children 15% to 20% Savings on Laser Surgery Online member services – www.vsp.com

18. Flexible Spending Account Administered by ADP Plan Year is not on the Calendar Year May 1st – April 30th Health Care Reimbursement Account Pre-tax deductions to pay for out-of-pocket medical expenses $5,000 annual maximum Claim can be submitted as soon as expense is incurred Dependent Care Reimbursement Account Pre-tax deductions to pay for dependent child and disabled adult daycare $5,000 annual maximum Claim can be submitted once expense is incurred AND funds deposited

19. How Does a Flexible Spending Account Work? Calculate expected expenses for the Plan Year (not the Calendar Year) Claims must be incurred during Plan Year while actively participating ADP offers a debit card 90 days to submit claims after end of plan year Unused funds will be forfeited to plan expenses Use it or lose it is an IRS rule

20. Medical Plans & Cost Employees only pay Dental premium contribution when medical coverage is waived. Medical enrollment elections must match dental enrollments. e.g.: family medical = family dental

21. Financial Accumulation & Income Protection

22. Financial and Income Benefits

23. Basic Life / AD&D Underwritten by UNUM 100% Employer paid benefit Employees covered for 2 times your annual earnings up to maximum of $600,000 Additional benefits Accelerated benefit for terminal illness Individual conversion available

24. Disability Benefits Underwritten by UNUM 100% Employer Paid Benefit Short-Term Disability Benefit is 66 2/3% of weekly earnings to $3,500 in coordination with state disability benefits when applicable 7 calendar days elimination period then up to 12 weeks of benefits 5 business days of elimination period paid full wages by GHI Long-Term Disability Picks up where STD leaves off Benefit is 66 2/3% of monthly earnings to $15,000 Benefits begin after 90 day elimination period

25. Voluntary Supplemental Life Underwritten by UNUM Why consider additional life insurance? Financial obligations Replacement of lost income upon a spouse's death Future family needs 100% employee paid • Guaranteed issue coverage available during initial enrollment • $150,000 employee ; $30,000 spouse ; $10,000 Child(ren) • Voluntary Accidental Death and Dismemberment (AD&D) also available. • Portable coverage

26. Voluntary Supplemental LTD Underwritten by UNUM Why consider additional supplemental individual disability insurance (IDI) plan? Higher income replacement, up to 75% of your total income Tax free benefit You own it – this policy is portable 100% Employee Paid • It’s voluntary coverage you pay with post-tax dollars so benefits are tax free under current tax laws. • It’s offered at a discounted rate because you're buying through Genomic Health, Inc. • It supplements your group long term disability coverage and can protect a higher percentage of your income. • During this enrollment, no medical exam is required for eligible employees who are actively at work. You will be asked a few eligibility questions. • The individual disability insurance policy belongs to you, even if you change jobs.

27. 401(k) Administered by Securian You are eligible 1 month after your hire date You will be automatically enrolled at 2% unless you log in and opt out Company match of $1,000 per year on a per pay period basis in 24 installments up to a maximum of $41.67 per pay period The Genomic Health match is in addition to the IRS limits. Therefore, in 2010, if you were to contribute the IRS max of $16,500 to the plan and GHI contributes a match of $1,000, you would have $17,500 in your account, tax deferred, by end of December 2010 Log in to www.securianretirementcenter.com to opt out or make changes to your contribution rate

28. 401(k) Current IRS Maximum contribution is $16,500 Additional $5,500 Catch-up For Those Age 50 and Older *IMPORTANT*: Subtract amount set aside in previous plan from annual maximum as there are serious tax implications if you over contribute 401(k) vesting is 25% per year over four years Contributions grow tax-free until withdrawn Plans Are Portable

29. Commuter Checks Administered by Human Resources Use them to purchase train, bus, Bart or other qualified purchases IRS Limit of $230 a month Pre-Tax salary deduction Money is deducted from your paycheck before taxes are taken out Commuter Checks are given to you the beginning of each month following your first deduction Complete your enrollment in BeneTrac For CA Employees only

30. Other Benefits

31. Time Off Refer to the Time Off Policies on the intranet Vacation accrues immediately, up to 15 days in your first year. An additional day is granted every year thereafter 2 Floating holidays* granted upon hire 6 Sick days* granted upon hire To request vacation forward all requests to your Manager and Payroll using Ultipro *If your start date is after June 30th you receive half

32. Worldwide Emergency Travel Assist Offered by UNUM Valid for business or pleasure Hospital admission guarantee Emergency medical evacuation Medically supervised transportation home Transportation for a friend or family member to join hospitalized patient Prescription replacement assistance Medical referrals to Western-trained, English-speaking medical providers Care and transport of unattended minor children All eligible employees will receive an Assist America wallet card containing contact information for in or outside the U.S.

33. Enrolment & Tools

34. How to Enroll in BeneTrac Review your benefit options You will receive BeneTrac log in instructions by your 2nd day You have 31 days to enroll in benefits Review and update your personal/demographic information Add / delete dependents Review or Change your Life / AD&D beneficiary Click “Review & Finalize” all benefits If declining benefits it is still required that you log in and decline

35. Where to Find BeneTrac Link HR Office – Benefits - BeneTrac Click here Click here

36. Where to Find Forms and Summary Plan Descriptions (SPDs)

37. Resources and Tools Your HR Benefits Team Employee Benefits Guide GHI Human Resources Intranet for information under Resources Benefit Website – BeneTrac https://www.eenroller.net/login.asp?ST=GENO9114 Willis Benefits Helpline (408) 436-7013 genomichealth@willis.com = Advocate for claim issues and benefit questions Member Services & 800 Customer Care #’s for all benefits

38. GHI Intranet, Compensation, Policies & Forms

39. Compensation Philosophy GHI’s compensation philosophy is designed to: Attract, retain, motivate and reward unique and high quality talent Reinforce a work culture infused with our values that supports our Three Circles Focus people on the achievement of crucial business objectives Reward for performance and results Allow employees to share in the success of the company Balance the needs of the individual with the needs of the company How? By providing employees with a competitive mix of pay, stock, and benefits, along with a great working environment and professional growth opportunities By building a global philosophy while aligning programs to competitive country practice By paying for performance and results

40. Focal Compensation Review Competitive compensation is a key component in GHI’s comprehensive Rewards and Recognition strategy To remain competitive, base salaries, bonus payouts, and stock are reviewed using external market data during a focal managerial review process This review process provides an opportunity for managers to make equitable and appropriate base salary increases for eligible employees at one time Conducting base salary reviews at a focal point in time also provides an opportunity to consider employee pay individually, within functional groups, and across GHI Compensation events February – Bonus payment, Focal salary review, promotions and adjustments, stock grants August – Bonus payment, Promotions and adjustments

41. Rewards and Recognition Program Genomic Health believes recognizing our employees for exceptional effort is an effective way to reinforce our values, encourage team work, and further motivate employees to strive for excellence The Spot Award program allows employees and managers to recognize contributions by providing immediate recognition for extra efforts that go above and beyond the normal expectations of the job  There are three different types of awards that allow our employees to recognize each others accomplishments: Bobble Head Spot Awards Hero of the Day Spot awards Team awards See the GHI intranet for eligibility and information

42. GHI Bonus Plan GHI's Bonus Plan is a semi-annual, variable pay program that recognizes company, individual and team performance aligned to the corporate goals Directors and above are paid annually Create individual S-M-A-R-T goals See the GHI intranet for policy, guidelines and philosophy and the corporate goals for the half Next Steps: Meet with your manager to set goals and record in SuccessFactors. You will be receiving login information via email.

43. Payroll Employees are paid semi-monthly 15th and last day of month Direct deposit is immediate UltiPro = self-service tool Access will be emailed to you View payroll statements Make demographic and payroll changes Vacation requests

44. Training Compliance & HIPAA Training Genomic Health is committed to compliance with applicable Federal, State and local statutes and regulations that affect the operation of its business in its role as a provider of health care services, in order to ensure that it is conducting its activities with the highest level of integrity and in accordance with law.  The development of this Compliance Program furthers that mission by insuring effective internal controls that promote adherence to applicable federal and state law. Training Assignments You will be receive your new hire trainings assignment by e-mail. It is required that you complete all assigned online Compliance, HIPAA, Health & Safety and Sexual Harassment training within 30 days from the date assigned. HIPAA & Compliance Certifications Return certifications to HR upon completion of your training assignments. These documents are available on the intranet and are also embedded in your Compliance and HIPAA trainings. For training related questions contact Carolyn Pasquarella or email trainingquestions@genomichealth.com

45. HR Systems • View and print pay stubs • Make address changes • View vacation balances • Request time off • Make tax withholding changes • Change Direct deposit withholding amounts or add bank accounts • Benefits Administration • New Hire Benefits Enrollment • Open Enrollment • Life Change Events • Compensation Administration: Focal Salary Review, Promotions, Bonuses, Stock Grants • Goal Management: S-M Goals, Cross functional view

46. Benefits and Employment Documents Due to HR

47. Where to find policies and Practices Click here

48. Where to find links to resources Click here

49. Thanks Thanks for taking the time to listen. We hope we have provided you with enough information to make informed benefits decisions as well as a good basic level of HR related information Contact HR with any questions you may have Francisca Epie – x2839 fepie@genomichealth.com Evangeline Mendiola – x2225 emendiola@genomichealth.com