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SH2D1A Regulates T-dependent Humoral Autoimmunity Jonathan D. Hron, Liron Caplan, Andrea J. Gerth, Pamela L. Schwartzb

Figure 1. SH2D1A-deficient mice are protected from experimentally induced lupus. 6?8-wk-old SH2D1A-deficient (KO) or -sufficient (WT) mice were injected intraperitoneally with 0.5 ml pristane (P) or PBS (S, saline). (A and B) 5 mo later, sera were assayed and titered for the presence of ANAs (ANA).

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SH2D1A Regulates T-dependent Humoral Autoimmunity Jonathan D. Hron, Liron Caplan, Andrea J. Gerth, Pamela L. Schwartzb

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