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NEN_71_10_2012_07_31_ERREDE_200889_SDC5

tyler-reilly
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NEN_71_10_2012_07_31_ERREDE_200889_SDC5

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  1. Supplementary Figure 5. Apparently normal cerebral cortex areas of EAE-affected mice stained for myelin basic protein (MBP) and claudin-5 (a) or visualized by FITC-dextran (b-d). a: A reconstruction of 3 fields shows apparently normal (arrows) and altered (arrowheads) claudin-5 junctional patterns in microvessels of a strongly MBP-reactive area; note the claudin-5 staining of a pial microvessel (asterisk). b-d: Microvessel leakage (arrows in b and d) and apparently unaffected microvessels (arrowheads in c and d) revealed by luminal FITC-dextran. Scale bars: 25 µm.

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