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RNA viruses: genome replication and mRNA production BSCI 437 Lecture 12

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RNA viruses: genome replication and mRNA production BSCI 437 Lecture 12

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    1. RNA viruses: genome replication and mRNA production BSCI 437 Lecture 12 Mechanisms of viral RNA synthesis Switch from mRNA to genomic RNA production General comments All RNA viral genomes must be efficiently copied to provide Genomes for assembly into progeny virions mRNAs for synthesis of viral proteins. Two essential requirements common to RNA virus infectious cycles: RNA genome copied end to end without loss of sequence Production of (cellular) translation-competent mRNAs.

    2. General strategies for replication and mRNA synthesis of RNA virus genomes. (See Fig 6.1)

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