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Anthropometry and Breast Cancer Publication. van den Brandt, P.A., et al. Pooled analysis of prospective cohort studies on height, weight and breast cancer risk. American Journal of Epidemiology. 2000; 152: 514-527. Cohort Studies in the Pooled Analysis of Anthropometry and Breast Cancer.
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Anthropometry and Breast Cancer Publication van den Brandt, P.A., et al. Pooled analysis of prospective cohort studies on height, weight and breast cancer risk. American Journal of Epidemiology. 2000; 152: 514-527.
Cohort Studies in the Pooled Analysis of Anthropometry and Breast Cancer Sweden Mammography Cohort Nurses’ Health Study Canadian National Breast Screening Study Netherlands Cohort Study New York State Cohort Adventist Health Study Total = 337,819 # cases = 4,385 Premeno. = 723 Postmeno. = 3,208 Iowa Women’s Health Study
Number of Cases in the Pooled Analysis of Anthropometry and Breast Cancer Study No. of cases Premeno. Postmeno. Adventist Health 20 87 Canadian National 122 242 Iowa Women’s 0 643 Netherlands Cohort 0 420 New York State 0 358 Nurses’ Health (a) 383 571 Nurses’ Health (b) 130 613 Sweden Mammography 68 274 van den Brandt et al, 2000
Pooled Multivariate Relative Risks for Breast Cancer and Body Mass Index BMI (kg/m2) RR (95% CI) Premenopausal Postmenopausal <21 1.00 (ref) 1.00 (ref) 21-<23 1.24 (0.97-1.57) 1.14 (0.99-1.33) 23-<25 1.03 (0.78-1.35) 1.15 (1.00-1.34) 25-<27 1.08 (0.79-1.48) 1.26 (1.09-1.47) 27-<29 0.97 (0.66-1.44) 1.43 (1.21-1.67) 29-<31 0.96 (0.60-1.52) 1.21 (1.01-1.46) 31-<33 0.55 (0.26-1.15) 1.29 (1.03-1.60) >33 0.58 (0.34-1.00) 1.27 (1.03-1.55) p for trend 0.007 0.001 p-for-interaction = 0.004 van den Brandt et al, 2000
Study-Specific Relative Risks for Premenopausal Breast Cancer and BMI Canada Nurses' (a) Nurses' (b) Sweden Combined 1 5 .5 Relative Risk van den Brandt, et al. 2000
Study-Specific Relative Risks for Postmenopausal Breast Cancer and BMI Adventist Canada Iowa Netherlands NY State Nurses' (a) Nurses' (b) Sweden Combined .8 1 2 Relative Risk van den Brandt, et al. 2000
Body Mass Index and Breast Cancer: Pooled Analysis van den Brandt et al, 2000
Pooled Multivariate Relative Risks for Breast Cancer and Height by Menopausal Status Height (m) Premenopausal Postmenopausal <1.60 1.00 (ref) 1.00 (ref) 1.60-<1.65 1.21 (0.94-1.55) 1.09 (0.98-1.21) 1.65-<1.70 1.06 (0.82-1.36) 1.23 (1.11-1.37) 1.70-<1.75 1.14 (0.86-1.52) 1.24 (1.09-1.41) >1.75 1.42 (0.95-2.12) 1.28 (0.94-1.76) p for trend 0.41 <0.001 p-for-interaction = 0.13 van den Brandt et al, 2000
Study-Specific Relative Risks for Premenopausal Breast Cancer and Height Canada Nurses' (a) Nurses' (b) Sweden Combined .6 1 2 Relative Risk van den Brandt et al, 2000
Study-Specific Relative Risks for Postmenopausal Breast Cancer and Height Adventist Canada Iowa Netherlands NY State Nurses’ (a) Nurses’ (b) Sweden Combined .8 1 2 Relative Risk van den Brandt, et al. 2000
Pooled Multivariate Relative Risks for Breast Cancer and Height Relative Risk Height (m) van den Brandt et al, 2000
Height and Breast Cancer: Pooled Analysis Van den Brandt et al, 2000 van den Brandt et al, 2000