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NEONATAL PULMONARY GRAPHICS ART OF VENTILATION IN TO SCIENCE OF VENTILATION Dr Vishram Buche Director, NICU Central India’s CHILD hospital & Research institute, NAGPUR
OBJECTIVES ……….. • How to identify different WAVES and LOOPS ? • and differentiate between normal and abnormal ? • How it helps to identify the mode of Vent ? • How it helps to adjust vent settings / vent circuits ? • How it helps to manage disease pattern ? • I. Progression • 2. Responding to drugs.. • 3. Deterioration • How it helps to identify / quantify the problem? • still many more……..
Measured Parameters…. • Flow • Pressure • Time Calculated Parameters ….. • Volume (as an integration of flow) • Compliance • Resistance • Work of Breathing • Auto-PEEP
Measurement of Flow……… • How it is Measured?....... • 1 Pressure Differential Pneumotachometer • 2 Hot Wire Anemometer • Where it is measured? …. • 1. At ETT • 2. Inside the ventilator
Measurement of Pressure…… • Where is it Measured? • At ETT • In Esophagus • Inside Ventilator
Basics phase variables………….. A. Trigger ……. • What causes the breath to begin? B. Limit …… • What regulates gas flow during the breath? C. Cycle ……. • What causes the breath to end? B C A
The Pulmonary graphics display in two formats……… …………………… Waveforms..!!! …………………….Loops ..!!!
Most Commonly used Waveforms and Loops…… Pressure vs. Time Flow vs. Time Volume vs. Time AND Pressure – volume loop Flow – volume loop Flow - pressure loop…???
Differentiate………….. Spontaneous Breaths…. Mechanical Breaths…. volume Time Pressure FLOW
Types of Waveforms…… Pressure Modes Volume Modes Pressure Flow Volume Time
Pressure Mode Pressure Flow Volume Time
Common features of Scalar WAVE forms….. Scalars…….. on ordinate (vertical), Time…………on Abscissa (horizontal) Time line…BASE line where P, F and V are at zero level (FRC or basal alveolar level) Elevated base line only when CPAP/ PEEP is there.
Common features of Scalar WAVE forms….. Inspiratory phase….Active…. affected by modes of vent. Expiratory phase….Passive NOT affected by mode of vent but by various characteristics of Resp system e.g. Resistance , compliance BUT.. Insp time can affect the duration of exp phase eg. In inverse ratio I:E
Common features of Scalar WAVE forms….. • While analyzing one has to keep in mind general • principles of EXPONENTIAL functions applied to • WAVEFORM graphics • Each waveform has to be analyzed in terms of • Magnitude, • Duration, • Pattern.
FLOW waveform……… Pressure mode Volume controlled PIF Flow Inspiration TE Zero flow TI Time Expiration Spont Br PEF What is flow?? How related to volume??
PRESSURE TIME waveform……… Pressure mode Volume controlled PIP Insp Exp Pressure Spont breath End Ex Pres PEEP Ti TE Time
Inspiratory Tidal Volume VOLUME TIME waveform ………. Pressure mode Volume controlled Expiration Inspiration Volume Spont. TI TE Time
Variations and Abnormalities in waveforms…!!!! FLOW-TIME waveform…………….. PRESSURE – TIME waveform……. VOLUME-TIME waveform………….
P Pressure Modes Pressure Flow Volume Time
FLOW waveform……… Pressure mode PIF Flow Inspiration TE Zero flow TI Time Expiration PEF
Identifies type of ventilation……………………… pressure vs. volume Pressure… Volume….
Abnormalities of Flow waveform……… Inspiratory flow pattern…… I -time 1 2 1 : short 2 : Normal 3 : Prolonged 3 Clinical significance……. ? Affects Tidal volume delivery Optimize Insp time
Fixed I –time.. ……..prolonged Flow termination sensitivity on
FLOW TERMINATION……Inspiratory Cycle Off…… 100% of Patient’s Peak Inspiratory Flow 100% 75% 50% Flow 30% • In the above example, the machine is set to cycle inspiration off at 30% of the patient’s peak inspiratory flow.
Inspiratory Cycle Off…… Exhalation spike A B 100% 100% 60% 10% Flow –termination classically seen in PSV……..
Flow Cycling Set PS level Identify mode….. PSV…… Patient Triggered, Flow Cycled, Pressure limited Mode Flow (L/m) Pressure (cm H2O) Volume (mL) Time (sec)
Normal Patient Air Trapping……… AUTO PEEP Inspiration Time Flow (L/min) Air-trapping AUTO PEEP Expiration When expiratory flow doesn’t return to base line………and inspiration starts before exp ends….
Where we can find air-trapping…..? • Pressure wave: while performing an expiratory hold, the waveform rises above baseline. • Flow wave: the expiratory flow doesn’t return to baseline before the next breath begins. • Volume wave: the expiratory portion doesn’t return to baseline. • Flow/Volume Loop: the loop doesn’t meet at the baseline • Pressure/Volume Loop: the loop doesn’t meet at the baseline
Auto-PEEP……. • Auto-PEEP = The averaged pressure by trapped gas in different lung units • A dynamic entity may not present in all breath • Short TE air entrapment • TEshorter than 3 expiratory time constant • So it is a potential cause of hyperinflation
Response to Bronchodilator…. After Before Long TE Shorter TE Flow Time PEFR Improved PEFR To assess response to bronchodilator therapy,…. 1. An increase in peak expiratory flow rate. 2. The expiratory curve should return to baseline sooner. Where else it can be observed…..??
3 2 1 . V 1 2 3 Bronchodilator Response….. F-V loop AFTER Relief Bronchospasm Normal 3 3 2 2 1 1 . . V LPS VT V 1 1 2 2 3 3
PRESSURE waveform……… Pressure mode PIP Insp Exp Pressure End Ex Pres PEEP Ti TE Time
PRESSURE waveform……… To Increase Mean Airway Pressure…. 1. Increase flow 2. Increase peak pressure 3. Lengthen inspiratory time 4. Increase PEEP 5. Increase Rate MAP….. PIP Pressure PEEP Ti TE Time
Identifying type of Breath/ mode of vent………….. Assisted Controlled Pressure Time
Identify vent mode…. P Interpret the mode: Mode Pressure support/CPAP The pressure waveform has a plateau The flow waveform doesn't return to baseline Is it a Volume or Pressure mode? Is it a Control or Support mode?
Identify vent mode…. Interpret the mode: Is it a Volume or Pressure mode? Is it a Control or Support mode?
Flow (L/min) Pressure (cm H2O) Volume (ml) SIMV + PS + CPAP Pressure control ventilation Identify mode……? Set P level Set P level CPAP level Time (sec)
Inspiratory Tidal Volume VOLUME waveform ………. Pressure controlled Expiration Inspiration Volume TI TE Time
How does it help…….??? • Air Leaks • Setting appropriate I-time • Weaning • Active Exhalation
Air Leak………… Volume (ml) Air Leak Time (sec) A = exhalation that does not return to zero
Where to look……? Endotracheal Tube Leaks…… Volume waveform Pressure-volume loop Flow-volume loop
Air Leak………… P-V loop Volume waveform…. V 30 VT ml P -10 F V F-V loop
Setting Appropriate I-Time ………. ……to get desired VT PCV…. PIP= 20, Vt (achieved) = 15 15 cc volume 0 1 2 3 4 5 6 Time Flow 1 2 3 4 5 6 Time Short I – time ……low Vt
Setting Appropriate I-Time ………. 15 cc 20 cc volume 0 1 2 3 4 5 6 Lost VT Flow 4 1 2 3 5 6 Time Appropriate I – time ……good Vt
Volume waveform … trending..guides for weaning PCV… SIMV A….Ineffective tidal volume in spontaneous breaths; B….Improved tidal volume during spontaneous breaths.
Active Exhalation…….. Volume (ml) Time (sec)
The volume waveform is most commonly used to assess which two conditions? Answer: Air trapping and leaks